胡霁    助理教授、研究员
所在学院生命科学与技术学院
研究方向行为的神经环路机制
联系方式huji@@shanghaitech.edu.cn


 
 个人简介 
2003年本科毕业于华中科技大学,同年进入中科院上海神经科学研究所。2005年随导师实验室转至北京生命科学研究所(NIBS)/中科院生物物理研究所,2008年获神经生物学博士学位。2009年开始在麻省理工学院Picower学习与记忆研究所(The Picower Institute for Learning and Memory at MIT )进行博士后研究工作。2013年1月回国,任职西安交通大学前沿科学技术研究院。2014年4月加入上海科技大学生命科学与技术学院任助理教授、研究员。
 主要研究内容 
我们发展和应用光学成像、神经调控、遗传学标记与神经环路示踪等最新的方法精确地研究情感及其相关的精神类疾病的重要科学问题。实验室拥有国际领先且全面的光学成像仪器(双光子显微镜、梯度折射透镜、光纤光度测量)和技术手段,同时也将结合单细胞测序,质谱技术等前沿的分子生物学手段,深入研究以下重要的神经科学问题:1.应激/压力的神经机制;2.神经精神药理的环路机制;3. 神经与精神疾病治疗的新策略。我们的研究将有助于重要的精神疾病比如抑郁症、焦虑症的治疗。
 代表性论文 

Research Articles *系通讯作者)

1. Shouhua Zhang; Fei Lv; Yuan Yuan; Chengyu Fan; Jiang Li; Wenzhi Sun; Ji Hu*, Whole-brain Mapping of Monosynaptic Afferent Inputs to Cortical CRH Neurons, Frontiers in Neuroscience (2019)

2. Zheng-dong Zhao; Zongming Chen; Xinkuan Xiang; Mengna Hu; Hengchang Xie; Xiaoning Jia; Fang Cai; Yuting Cui; Zijun Chen; Lechen Qian; Jiashu Liu; Congping Shang; Yiqing Yang; Xinyan Ni; Wenzhi Sun; Ji Hu; Peng Cao; Haohong Li; Wei L Shen, Zona incerta GABAergic neurons integrate prey-related sensory signals and induce an appetitive drive to promote hunting, Nature Neuroscience (2019)

3. Haibin Zhou; Shouhua Zhang; Fei Lv; Wenzhi Sun; Lihua Wang; Chunhai Fan; Jiang Li*; Ji Hu*, Citrateassisted efficient local delivery of naked oligonucleotide into live mouse brain cells, Cell Proliferation, 2019, e12622

4. Xin-Yu Su; Ming Chen; Yuan Yuan; Ying Li; Su-Shan Guo; Huo-Qing Luo; Huang Cheng; Wenzhi Sun; Yong Li; Michael X. Zhu; Ming-Gang Liu*Ji Hu*; Tian-Le Xu*, Central Processing of Itch in the Midbrain Reward Center, Neuron (2019)

5. Yuan Yuan; Wei Wu; Ming Chen; Fang Cai; Chengyu Fan; Wei Shen; Wenzhi Sun*Ji Hu*, Reward Inhibits Paraventricular CRH Neurons to Relieve Stress, Current Biology, 2019, 29: 1~9

6. Rongfeng Hu; Juen Zhang; Minmin Luo; Ji Hu*, Response Patterns of GABAergic Neurons in the Anterior Piriform Cortex of Awake Mice, Cerebral Cortex, 2017.6.1, 27(6): 3110~3124

7. Rongfeng Hu; Sen Jin; Xiaobin He; Fuqiang Xu; Ji Hu*, Whole-Brain Monosynaptic Afferent Inputs to Basal Forebrain Cholinergic System, Frontiers in Neuroanatomy, 2016.10.10, 10: 0~98

8. Andrii Rudenko; Jinsoo Seo; Ji Hu; Susan C Su; Froylan Calderon de Anda; Omer Durak; Maria Ericsson; Marie Carlén; Li-Huei Tsai, Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment, Journal of Neuroscience (2015)

9. Tao Chen, Kohei Koga, Giannina Descalzi, Shuang Qiu, Jian Wang, Le-Shi Zhang, Zhi-Jian Zhang, Xiao-Bin He, Xin Qin, Fu-Qiang Xu, Ji Hu, Feng Wei, Richard L Huganir, Yun-Qing Li; Min Zhuo,Postsynaptic potentiation of corticospinal projecting neurons in the anterior cingulate cortex after nerve injury, Molecular Pain, 2014, 10:33

10. Rong Gong#; Cheng Ding#; Ji Hu#; Yao Lu; Fei Liu; Elizabeth Mann; Fuqiang Xu,; Mitchell B. Cohen; Minmin Luo, Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior, Science, 2011.9.16, 333(6049): 1642~1646 (#co-first author)

11. Lili Gao; Ji Hu; Chun Zhong; Minmin Luo, Integration of CO2 and odorant signals in the mouse olfactory bulb, Neuroscience, 2011, 3(27):881-892

12. Ji Hu#; Chun Zhong#; Cheng Ding; Qiuyi Chi; Andreas Walz; Peter Mombaerts; Hiroaki Matsunami; Minmin Luo(*), Detection of near-atmospheric concentrations of CO2 by an olfactory subsystem in the mouse, Science, 2007.8.17, 317(5840): 953~957(#co-first author)

13. Liming Sun; Huayi Wang; Ji Hu; Jinlong Han; Hiroaki Matsunami; Minmin Luo, Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate, Proceedings of the National Academy of Sciences of the United States of America, 2009.2.10, 106(6): 2041~2046

  

Review article*系通讯作者)

14. Fang Luo; Yin Wei; Ziyue Wang; Minmin Luo; Ji Hu*, Genetically encoded neural activity indicators, Brain Science Advances, (2018)

15. Yan Yang; Hao Wang; Ji Hu*; Hailan Hu*, Lateral habenula in the pathophysiology of depression, Current Opinion in Neurobiology, 2018.02, 48: 90~96, (*co-corresponding author)

16. Minmin Luo; Liming Sun; Ji HuNeural detection of gases--carbon dioxide, oxygen--in vertebrates and invertebratesCurrent Opinion in Neurobiology, 2009.8, 19(4): 354~361 

                                 

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