钟桂生    助理教授、研究员
所在学院生命科学与技术学院
研究方向神经生物学,超分辨光学
联系方式zhongsh@@shanghaitech.edu.cn
备注青年千人
 
 个人简介 
1999年本科毕业于安徽大学;2002年硕士毕业于中国科学技术大学;2007年康奈尔大学获博士学位;2007-2015年,先后在康奈尔大学和哈佛大学从事博士后研究。2015年加入上海科技大学iHuman研究所任Research Associate Professor, PI,加入上海科技大学生命科学与技术学院任助理教授、研究员。
 主要研究内容 
课题组将结合超分辨显微成像、电生理等方法具体研究以下相关的生物学问题:1. GPCR在细胞中的结构和功能;2.控制运动行为的神经环路机制;3.小胶质细胞与神经元之间的相互作用机制。同时我们发展应用STORM, X-ray新的超分辨细胞成像方法。
 代表性论文 
(1) Zhong G#, He J#, Zhou R, Lorenzo DN, Babcock HP, Bennett V & Zhuang X. (2015) The formation of a periodic cytoskeleton structure in neurons during development. Elife e04581.

(2) Xu K#, Zhong G # & Zhuang X. (2013) Actin, spectrin, and associated proteins form a periodic cytoskeletal structure in axons. Science 339: 452-456.

(3) Shim SH, Xia C, Zhong G , Babcock HP, Vaughan JC, Huang B, Wang X, Xu C, Bi G-Q & Zhuang X. (2012) Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes. PNAS 109: 13978-13983.

(4) Zhong G , Shevtsova NA, Rybak IA & Harris-Warrick RM. (2012) Neuronal activity in the isolated mouse spinal cord during spontaneous deletions in fictive locomotion: Insights into locomotor CPG organization. J Physiol 590: 4735-4759

(5) Abbinanti MD, Zhong G & Harris-Warrick RM. (2012) Postnatal Emergence of Serotonin-Induced Plateau Potentials in Commissural Interneurons of the Mouse Spinal Cord. J Neurophysiol 108: 2191-2202.

(6) Zhong G , Sharma K & Harris-Warrick RM. (2011) Frequency-dependent recruitment of V2a interneurons during fictive locomotion in the mouse spinal cord. Nature Commun 2: 274.

(7) Zhong G , Droho S, Crone S, Dietz S, Kwan A, Webb WW, Sharma K & Harris-Warrick RM. (2010) Electrophysiological characterization of the V2a interneurons and their locomotor-related activity in the neonatal mouse spinal cord. J Neurosci 30: 170-182.

(8) Kwan AC, Dietz SB, Zhong G , Harris-Warrick RM & Webb WW. (2010) Spatiotemporal dynamics of rhythmic spinal interneurons measured with two-photon calcium imaging and coherence analysis. J Neurophysiol 104: 3323-3333.

(9) Crone S#, Zhong G #, Harris-Warrick RM & Sharma, K. (2009) In mice lacking V2a interneurons, gait depends on speed of locomotion. J Neurosci 29: 7098-7109.

(10) Zhong G , Masino MA & Harris-Warrick RM. (2007) Persistent sodium currents participate in fictive locomotion generation in neonatal mouse spinal cord. J Neurosci 27: 4507-4518.                                    

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