钱友存    特聘教授
所在学院生命科学与技术学院
中科院上海生命科学研究院健康科学研究所
研究方向分子免疫学(中科院上海生命科学研究院健康科学研究所研究员)
联系方式ycqian@@sibs.ac.cn
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 主要研究内容 
通过小鼠动物模型结合临床病人样本研究炎症相关重大疾病(包括自身免疫病、感染性疾病、肿瘤、糖尿病等)的细胞和分子机制。
 代表性论文 
                                        1. Song X, Gao H, Lin Y, Yao Y, Zhu S, Wang J, Liu Y, Yao X, Meng G, Shen N, Shi Y, Iwakura Y, Qian Y*. Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis. Immunity. 2014 Jan 16;40(1):140-52. <
2. Song X, Qian Y*. Peli1 sets the CNS on fire. Nat Med. 2013 May;19(5):536-8.<
3. Zhu S, Pan W, Song X, Liu Y, Shao X, Tang Y, Liang D, He D, Wang H, Liu W, Shi Y, Harley J, Shen N* and Qian Y*.. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α. Nat. Med. (2012)18(7)1077-1086. <
4. Song X, Zhu S, Shi P, Liu Y, Shi Y, Levin SD, Qian Y*.. IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat. Immunol., 12(12):1151-8. (2011).<
5. Zhu S, Pan W, Shi P, Gao H, Zhao F, Song X, Liu Y, Zhao L, Li X, Shi Y, Qian Y*. Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling. J. Exp. Med., 207(12):2647-62. (2010) <

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