柳振峰    特聘教授
所在学院生命科学与技术学院
中科院生物物理研究所
研究方向膜蛋白结构生物学(中科院生物物理研究所研究员)
联系方式liuzf@@ibp.ac.cn
备注青年千人
 
 主要研究内容 
应用结构生物学为主的方法,如X-射线晶体学和冷冻电子显微学,研究重要生物学过程的分子机理,如光合作用中的状态转换过程、原核和真核细胞对于机械力信号的感应过程、以及磷脂生物合成和修饰过程。目标是基于三维结构,对参与重要生物学过程的关键膜蛋白的结构与功能进行深入研究,阐明其发挥作用的机制。
 代表性论文 
                                        1. Zhenfeng Liu, Troy A. Walton and Douglas C. Rees. A reported archaeal mechanosensitive channel is a structural homolog of the MarR-like transcriptional regulators. Protein Science, 19: 808-814 (2010).
2. Zhenfeng Liu, Chris S. Gandhi and Douglas C. Rees. Structure of a tetrameric MscL in an expanded intermediate state. Nature, 461: 120-124 (2009).
3. Zhenfeng Liu and Wenrui Chang. Structure of the light-harvesting complex II. In: Photosynthetic Protein Complexes. Fromme P. ed., 217-242, Wiley-VCH (2008) (Book chapter).
4. Zhenfeng Liu and Wenrui Chang. Crystallization Methods of Membrane Proteins: Practical Aspects of Crystallizing Plant Light-Harvesting Complexes. In: Biophysical Techniques in Photosynthesis II. Aartsma T. J. and Matysik J. eds. Vol 26, 77-96 Spinger (2008) (Book chapter).
5. Zhenfeng Liu, Hanchi Yan, Kebin Wang, Tingyun Kuang, Jiping Zhang, Lulu Gui, Xiaomin An & Wenrui Chang. Crystal structure of spinach major light-harvesting complex at 2.72 resolution. Nature 428, 287-292 (2004).                                    

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