蓝柯    特聘教授
所在学院生命科学与技术学院
中科院上海巴斯德研究所
研究方向肿瘤病毒学(中科院上海巴斯德研究所研究员)
联系方式lanke@@ips.ac.cn
备注杰青、百人
 
 主要研究内容 
人类重要肿瘤病毒--卡波氏肉瘤相关疱疹病毒(KSHV)潜伏感染与致病的机理研究。
 代表性论文 
                                        1. Zhao Q, Liang D, Sun R, Jia B, Xia T, Xiao H, Lan K*. Kaposi's Sarcoma-Associated Herpesvirus-Encoded Replication and Transcription Activator Impairs Innate Immunity via Ubiquitin-Mediated Degradation of Myeloid Differentiation Factor 88. J Virol. 2015 Jan 1;89(1):415-27.
2. Liang D, Hu H, Li S, Dong J, Wang X, Wang Y, He L, He Z, Gao Y, Gao SJ, Lan K*. Oncogenic herpesvirus KSHV Hijacks BMP-Smad1-Id signaling to promote tumorigenesis. PLoS Pathog. 2014 Jul 10;10(7):e1004253.
3. Sun R, Liang D, Gao Y, Lan K*. Kaposi's sarcoma-associated herpesvirus-encoded LANA interacts with host KAP1 to facilitate establishment of viral latency. J Virol. 2014 Jul;88(13):7331-44. Spotlight article.
4. Wang X, He Z, Xia T, Li X, Liang D, Lin X, Wen H, Lan K*. Latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus promotes angiogenesis through targeting notch signaling effector Hey1. Cancer Res. 2014 Apr 1;74(7):2026-37.
5. Lin X, Li X, Liang D, Lan K*. miRNAs and usRNAs Discovered in Kaposi's Sarcoma-associated Herpesvirus Virions. J Virol. 2012 Dec;86(23): 12717-30.

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