孔祥银    特聘教授
所在学院生命科学与技术学院
中科院上海生命科学研究院健康科学研究所
研究方向疾病易感基因识别和功能研究(中科院上海生命科学研究院健康科学研究所研究员)
联系方式xykong@@sibs.ac.cn
备注杰青、百人
 
 主要研究内容 
1. 人类重大疾病发生的遗传学和表现遗传学基础;2. 基因组变异规律的研究;3. 疾病相关基因的功能研究。
 代表性论文 
                                        1. Liu Y, Xu H, Chen S, Chen X, Zhang Z, Zhu Z, Qin X, Hu L, Zhu J, Zhao GP, Kong X. Genome-wide interaction-based association analysis identified multiple new susceptibility Loci for common diseases. PLoS Genet. 2011 Mar;7(3):e1001338. Epub 2011 Mar 17.
2. Zhang Z, Zhou L, Wang P, Liu Y, Chen X, Hu L, Kong X. Divergence of exonic splicing elements after gene duplication and the impact on gene structures. Genome Biol. 2009 Nov 2; 10(11):R120.
3. Yin S, Wang P, Deng W, Zheng H, Hu L, Hurst LD, Kong X. Dosage compensation on the active X chromosome minimizes transcriptional noise of X-linked genes in mammals. Genome Biol. 2009 Jul 13;10(7):R74.
4. Wang ZQ, Si L, Tang Q, Lin D, Fu Z, Zhang J, Cui B, Zhu Y, Kong X, Deng M, Xia Y, Xu H, Le W, Hu L, Kong X. Gain-of-function mutation of KIT ligand on melanin synthesis causes familial progressive hyperpigmentation. Am J Hum Genet. 2009 May;84(5):672-7.
5. Wang P, Yin S, Zhang Z, Xin D, Hu L, Kong X, Hurst LD .Evidence for common short natural trans sense-antisense pairing between transcripts from protein coding genes. Genome Biol. 2008;9(12):R169. Epub 2008 Dec 2.                                    

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