陈正军    特聘教授
所在学院生命科学与技术学院
中科院上海生命科学研究院生物化学与细胞生物学研究所
研究方向磷酸化蛋白质细胞信号网络与肿瘤发生(中科院上海生命科学研究院生物化学与细胞生物学研究所研究员)
联系方式zjchen@@sibcb.ac.cn
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 主要研究内容 
1. 细胞极性与细胞迁移、增殖和肿瘤发生的相关性研究;2. 酪氨酸激酶细胞信号通路研究;3. 磷酸化蛋白质组学研究。
 代表性论文 
1. Du D, Xu F, Yu L, Zhang C, Lu X, Yuan H, Huang Q, Zhang F, Bao H, Jia L, Wu X, Zhu X, Zhang X, Zhang Z, Chen Z*. The Tight Junction Protein, Occludin, Regulates the Directional Migration of Epithelial Cells. Developmental Cell. 2010, 18(1):52-63.
2. Yuan H, Zhang H, Wu X, Zhang Z, Du D, Zhou S, Brakebusch C, and Chen Z*. Hepatocyte-specific deletion of Cdc42 results in delayed liver regeneration after partial hepatectomy in mice. Hepatology. 2009, 49:240-249.
3. Lu XF, Feng XJ, Man XB, Yang G, Tang L, Du D, Zhang F, Yuan HX, Huang Q, Zhang Z, Liu YK, Strand D, and Chen Z*. Aberrant Splicing of Hugl-1, the Human Homologue of Drosophila Tumor Suppressor Gene lgl, is Associated with Hepatocellular Carcinoma Progression. Clin Cancer Res. 2009;15(10):3287-3296.
4. Feng X, Lu X, Man X, Zhou W, Jiang LQ, Knyazev P, Lei L, Huang Q, Ullrich A, Zhang Z*, and Chen Z*. Overexpression of Csk-binding protein (Cbp) contributes to renal cell carcinogenesis. Oncogene. 2009, 28(37):3320-31.
5. Yang G, Li Q, Ren S, Lu X, Fang L, Zhou W, Zhang F, Xu F, Zhang Z, Zeng R, Lottspeich F, and Chen Z*. Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins. Proteomics. 2009, 9(21):4944-61.                                    

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