陈雁    特聘教授
所在学院生命科学与技术学院
中科院上海生命科学研究院营养科学研究所
研究方向分子医学, 2型糖尿病和肿瘤发生的机制研究(中科院上海生命科学研究院营养科学研究所研究员)
联系方式ychen3@@sibs.ac.cn
备注杰青、百人
 
 主要研究内容 
运用分子生物学、细胞生物学和动物模型,研究营养代谢相关疾病和肿瘤发生过程中的细胞内信号转导、基因调控、以及病理生理学机制。
 代表性论文 
1. Wang, X., Wang, L., Zhu, L., Pan, Y., Xiao, F., Liu, W., Wang, Z., Guo, F., Liu, Y., Thomas, W.G., and Chen, Y. (2013) PAQR3 modulates insulin signaling by shunting phosphoinositide 3-kinase p110α to the Golgi apparatus. Diabetes. 62(2):444-456
2. Huang, H, Jin, T., He, J., Ding, Q., Xu, D., Wang, L., Zhang, Y., Pan, Y., Wang, Z., and Chen, Y. (2012) Progesterone and adipoQ receptor 11 links Ras signaling to cardiac development in zebrafish. Arteriosclerosis, Thrombosis, and Vascular Biology 32(9):2158-70
3. Jiang, Y., Xie, X., Li, Z., Wang, W., Zhang, Y., Ling, Z., Pan, Y., Wang. Z., and Chen, Y., (2011) Functional cooperation of RKTG with p53 in tumorigenesis and epithelial-mesenchymal transition. Cancer Research 71(8):2959-68
4. Luo, X., Zhang, Y., Ruan, X., Jiang, X., Zhu, L., Wang, X., Ding, Q., Liu, W., Pan, Y., Wang, Z., and Chen, Y. (2011) Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation on hepatic glycogenesis. Diabetes 60(5):1435-45
5. Yang, L., Zhang, Y., Wang, L., Fan, F., Zhu, L., Li, Z., Ruan, X., Huang, H., Wang, Z., Huang, Z., Huang, Y., Yan, X., and Chen, Y. (2010) Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22. Journal of Hepatology 53:339-47                                    

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