陈洛南    特聘教授
所在学院生命科学与技术学院
中科院上海生命科学研究院系统生物学重点实验室
研究方向计算系统生物学，计算生物学，生物信息学，复杂疾病分析（中科院上海生命科学研究院系统生物学重点实验室研究员）
联系方式lnchen@@sibs.ac.cn


 
 主要研究内容 
采用系统工程、动力学分析、优化和数学建模的方式，结合生物信息学和现代生命科学实验，以生物复杂网络和动态行为为主线来研究生命系统及复杂疾病问题。1. 网络系统生物学（Network Systems Biology）；2. 生物信息学（Bioinformat ics）；3. 计算系统生物学（Computational Systems Biology）；4. 复杂疾病分析（Complex Diseases）等方面的研究。
 代表性论文 
1. Luonan Chen*, Rui Liu, Zhi-Ping Liu, Meiyi Li, Kazuyuki Aihara. Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers. Scientific Reports, 2:342, 2012.
2. Hailong Zhu, R. Shyama Prasad Rao, Jiming Liu, Tao Zeng, Luonan Chen*. Reconstructing dynamic gene regulatory networks from sample-based transcriptional data. Nucleic Acids Research. Nucleic Acids Res. 2012. 40(21):10657-10667.
3. Xiujun Zhang, Xingming Zhao, Kun He, Le Lu, Yongwei Cao, Jingdong Liu, Jin-Kao Hao, Zhi-Ping Liu, Luonan Chen*. Inferring gene regulatory networks from gene expression data by path consistency algorithm based on conditional mutual information. Bioinformatics, 28(1):98-104, 2012.
4. Danning He, Zhiping Liu, Masao Honda, Shuichi Kaneko, Luonan Chen*. Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma. Journal of Molecular Cell Biology, 4(3):140-52, 2012.
5. Jiguang Wang, Qiang Huang, Zhi-Ping Liu, Yong Wang, Ling-Yun Wu, Luonan Chen*, Xiang-Sun Zhang. NOA: a novel Network Ontology Analysis method. Nucleic Acids Res. 2011. 39(13):e87.                                    

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