Ji Hu    Assistant Professor, PI
InstituteSchool of Life Science and Technology
Research AreaCircuit Mechanism of Emotion
Contact Info.huji@@shanghaitech.edu.cn


Biography
Dr. Ji Hu obtained his bachelor degree from Huazhong University of Science and Technology in 2003, and was accepted into the Institute of Neuroscience, Chinese Academy of Sciences in the same year. In 2005 he transferred to the National Institute of Biological Sciences (NIBS)/Institute of Biophysics, CAS in Beijing. Dr. Hu received his Ph.D. degree in neurobiology in 2008. In 2009, he started his postdoctoral training in Picower Institute for learning and memory at MIT. Dr. Hu returned to China to work at Xi’an Jiaotong University in 2013 and then joined the School of Life Science and Technology of ShanghaiTech University as assistant professor (Tenure-track), PI since April of 2014. Dr.Hu was selected to the “Young 1000 talented scholar” in 2014.

Research Interests
In subcortical nuclei, several types of projection neurons are intermingled and thus it is impossible to use traditional neurophysiological techniques to precisely record/manipulate/trace specific type of neurons. We are applying and developing several cutting-edge methods, by combining mouse genetics, vial transgenes, electrophysiology and optical imaging to functional dissection of subcortical circuitry. We are using these new methods to attack two related neurobiological questions, 1. Mammalian olfactory processing in higher brain areas. 2. Circuit mechanism of emotion. These researches may shed light on developeing new clinical interventions of psychiatric diseases, such depression and anxiety disorder.

Selected Publications
1. Hu R, Jin S, He X, Xu F and Hu J*. (in press) Whole-Brain Monosynaptic Afferent Inputs to Basal Forebrain Cholinergic System. Frontiers in Neuroanatomy (*correspondence author)

2. Hu R, Zhang J, Luo M, Hu J*. (in press) Response Patterns of GABAergic Neurons in the Anterior Piriform Cortex of Awake Mice. Cerebral Cortex (*correspondence author)

3. Gong R*, Ding C*, Hu J*, Lu Y, Liu F, Mann E, Xu F, Cohen MB and Luo M*. (2011) Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior. Science (*co-first author)

4. Sun L, Wan H, Hu J, Han J, Matsunami H, and Luo M (2009) Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate. PNAS

5. Hu J*, Zhong C*, Ding C, Chi Q, Walz A, Mombaerts P, Matsunami H, and Luo M(2007) Detection of near-atmospheric concentrations of CO2 by an olfactory subsystem. Science (*co-first author)


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