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Xingxu Huang, PhDProfessor

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Email: huangxx@@shanghaitech.edu.cn

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Principal investigator

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Xingxu HuangProfessor , PhD, Professor

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School of Life Science and Technology

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Group Introduction

Research Area:
Transcriptional and Epigenetic Regulation of Reprogramming and Lineage Commitment in Germ Cell Development
Research Interests:

The germ cell ensures the perpetuating and diversifying the genetic and epigenetic information across the generations. The germ cell development is accompanied by several fundamental biological processes such as reprogramming and lineage commitment which are regulated by transcriptional network and epigenetic modifications. After profiling the global transcriptome and epigenome, one of the next frontiers in biology is to site-specifically define and manipulate the transcriptional and epigenetic regulation of different biological processes. To this end, we have been developing genetic and epigenetic manipulation approaches, and applying such approaches combined with genome-wide analysis to understand the site-specific transcriptional and epigenetic regulation of germ cell development, including the elucidation and manipulation of the epigenetic and transcriptional network for reprogramming and lineage commitment.


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