陈佳

1. Li, Guangye*; Chen, Guo*; Yuan, Guo-Hua*; Wei, Jia; Ni, Qingyang; Wu, Jing; Yang, Bei; Yang, Li^#; Chen, Jia^#.Specific and efficient RNA A-to-I editing through cleavage of an ADAR inhibitor.Nature Biotechnology. 26 March 2025.

2. Fan, Yuhang*; Xu, Wenchao*; Gao, Bao-Qing*; Qin, Huichao; Wu, Xiaoyi; Wei, Jia; Ni, Qingyang; Zhou, Lina; Xiang, Jiangchao; Wu, Jing; Yang, Bei; Yang, Li; Chen, Jia^#;^#.Leveraging base excision repair for efficient adenine base editing of mitochondrial DNA.Nature Biotechnology. 25 March 2025.

3. Chen, Qimingxing*; Chang, Yan*; He, Xiaoyan; Ding, Yan; Wang, Runyuan; Luo, Ran; Yuan, Jialu; Chen, Jiabei; Zhong, Guisheng; Yang, Huiying; Chen, Jia^#; Li, Jianfeng^#.Targeted Delivery of mRNA with Polymer-Lipid Nanoparticles for In Vivo Base Editing.ACS Nano. 4 Mar 2025.

4. Han, Wenyan*; Qiu, Hou-Yuan*; Sun, Shangwu*; Fu, Zhi-Can*; Wang, Guo-Quan*; Qian, Xiaowen*; Wang, Lijie; Zhai, Xiaowen; Wei, Jia; Wang, Yichuan; Guo, Yi-Lin; Cao, Guo-Hua; Ji, Rui-Jin; Zhang, Yi-Zhou; Ma, Hongxia; Wang, Hongsheng; Zhao, Mingli; Wu, Jing; Bi, Lili; Chen, Qiu-Bing; Li, Zifeng; Yu, Ling; Mou, Xiaodun; Yin, Hao; Yang, Li^#; Chen, Jia^#; Yang, Bei^#; Zhang, Ying^#; .Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable off-target mutations in human HSCs.CELL STEM CELL. Nov 2023.

5. Kim, Jin-Soo^#*; Chen, Jia^#*; .Base editing of organellar DNA with programmable deaminases.NATURE REVIEWS MOLECULAR CELL BIOLOGY. 01 Oct 2023.

6. Han, Wenyan*; Gao, Bao-Qing*; Zhu, Junjie*; He, Zongxing*; Li, Jianfeng^#; Yang, Li^#; Chen, Jia^#; .Design and application of the transformer base editor in mammalian cells and mice.NATURE PROTOCOLS. 04 Oct 2023.

7. Zhao, Wenwen*; Li, Jifang*; Wang, Xiao*; Xu, Wei*; Gao, Bao-Qing*; Xiang, Jiangchao; Hou, Yaofeng; Liu, Wei; Wu, Jing; Qi, Qilian; Wei, Jia; Yang, Xiaoyu; Lu, Lu^#; Yang, Li^#; Chen, Jia^#; Yang, Bei^#; .Prime editor-mediated functional reshaping of ACE2 prevents the entry of multiple human coronaviruses, including SARS-CoV-2 variants.MEDCOMM. 2023.

8. Li, Xiaosa^#*; Zhou, Lina*; Gao, Bao-Qing*; Li, Guangye; Wang, Xiao; Wang, Ying; Wei, Jia; Han, Wenyan; Wang, Zixian; Li, Jifang; Gao, Runze; Zhu, Junjie; Xu, Wenchao; Wu, Jing; Yang, Bei; Sun, Xiaodong^#; Yang, Li^#; Chen, Jia^#; .Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure.NATURE COMMUNICATIONS. 29 Mar 2022. 13(1):1669.

9. Gao, Runze*; Fu, Zhi-Can*; Li, Xiangyang*; Wang, Ying*; Wei, Jia; Li, Guangye; Wang, Lijie; Wu, Jing; Huang, Xingxu^#; Yang, Li^#; Chen, Jia^#; .Genomic and Transcriptomic Analyses of Prime Editing Guide RNA-Independent Off-Target Effects by Prime Editors.CRISPR JOURNAL. Apr 2022. 5(2):276-293.

10. Li, Guanglei*; Li, Xiangyang*; Zhuang, Songkuan*; Wang, Liren*; Zhu, Yifan*; Chen, Yangcan*; Sun, Wen*; Wu, Zeguang*; Zhou, Zhuo; Chen, Jia^#; Huang, Xingxu^#; Wang, Jin^#; Li, Dali^#; Li, Wei^#; Wang, Haoyi^#; Wei, Wensheng^#*; .Gene editing and its applications in biomedicine.SCIENCE CHINA-LIFE SCIENCES. Apr 2022. 65(4):660-700.

11. Yang, Li^#*; Chen, Jia^#; .A Tale of Two Moieties: Rapidly Evolving CRISPR/Cas-Based Genome Editing.TRENDS IN BIOCHEMICAL SCIENCES. Oct 2020. 45(10):874-888.

12. Wang, Lijie*; Xue, Wei*; Zhang, Hongxia*; Gao, Runze*; Qiu, Houyuan*; Wei, Jia; Zhou, Lina; Lei, Yun-Ni; Wu, Xiaocheng; Li, Xiao; Liu, Chengfang; Wu, Jing; Chen, Qiubing; Ma, Hanhui; Huang, Xingxu; Cai, Cheguo; Zhang, Ying; Yang, Bei^#; Yin, Hao^#; Yang, Li^#; Chen, Jia^#; .Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations.NATURE CELL BIOLOGY. May 2021. 23(5):552-563.

13. Wang, Xiao*; Ding, Chengfeng*; Yu, Wenxia*; Wang, Ying*; He, Siting*; Yang, Bei*; Xiong, Yi-Chun; Wei, Jia; Li, Jifang; Liang, Jiayi; Lu, Zongyang; Zhu, Wei; Wu, Jing; Zhou, Zhi; Huang, Xingxu; Liu, Zhen^#; Yang, Li^#; Chen, Jia^#; .Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response.CELL REPORTS. 02 Jun 2020. 31(9).

14. Yang, Li^#*; Yang, Bei^#; Chen, Jia^#; .One Prime for All Editing.CELL. Dec 2019. 179(7):1448-1450.

15. Wang, Ying*; Gao, Runze*; Wu, Jing*; Xiong, Yi-Chun; Wei, Jia; Zhang, Sipin; Yang, Bei; Chen, Jia^#; Yang, Li^#; .Comparison of cytosine base editors and development of the BEable-GPS database for targeting pathogenic SNVs.GENOME BIOLOGY. Oct 2019. 20(1).

16. Chen, Jia^#*; Yang, Bei^#; Yang, Li^#; .To BE or not to BE, that is the question.NATURE BIOTECHNOLOGY. May 2019. 37(5):520-521.

17. Yang, Bei^#*; Yang, Li^#; Chen, Jia^#; .Development and Application of Base Editors.CRISPR JOURNAL. Apr 2019. 2(2):91-104.

18. Li, Jianan*; Liu, Zhen*; Huang, Shisheng*; Wang, Xiao; Li, Guanglei; Xu, Yuting; Yu, Wenxia; Chen, Shanshan; Zhang, Yu; Ma, Hanhui; Ke, Zunfu; Chen, Jia^#; Sun, Qiang^#; Huang, Xingxu^#; .Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome.CELL RESEARCH. Feb 2019. 29(2):174-176.

19. Wang, Xiao*; Li, Jianan*; Wang, Ying*; Yang, Bei*; Wei, Jia*; Wu, Jing; Wang, Ruixuan; Huang, Xingxu^#; Chen, Jia^#; Yang, Li^#; .Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion.NATURE BIOTECHNOLOGY. Oct 2018. 36(10):946-949.

20. Li, Xiaosa*; Wang, Ying*; Liu, Yajing*; Yang, Bei*; Wang, Xiao; Wei, Jia; Lu, Zongyang; Zhang, Yuxi; Wu, Jing; Huang, Xingxu^#; Yang, Li^#; Chen, Jia^#; .Base editing with a Cpf1-cytidine deaminase fusion.NATURE BIOTECHNOLOGY. Apr 2018. 36(4):324-327.

21. Lei, Liqun*; Chen, Hongquan*; Xue, Wei*; Yang, Bei*; Hu, Bian*; Wei, Jia; Wang, Lijie; Cui, Yiqiang; Li, Wei; Wang, Jianying; Yan, Lei; Shang, Wanjing; Gao, Jimin; Sha, Jiahao; Zhuang, Min; Huang, Xingxu; Shen, Bin^#; Yang, Li^#; Chen, Jia^#; .APOBEC3 induces mutations during repair of CRISPR-Cas9-generated DNA breaks.NATURE STRUCTURAL & MOLECULAR BIOLOGY. Jan 2018. 25(1):45-52.

22. Wang, Lijie*; Xue, Wei*; Yan, Lei*; Li, Xiaosa; Wei, Jia; Chen, Miaomiao; Wu, Jing; Yang, Bei^#; Yang, Li^#; Chen, Jia^#; .Enhanced base editing by co-expression of free uracil DNA glycosylase inhibitor.CELL RESEARCH. Oct 2017. 27(10):1289-1292.

23. Yang, Bei^#*; Li, Xiaosa; Lei, Liqun; Chen, Jia^#; .APOBEC: From mutator to editor.JOURNAL OF GENETICS AND GENOMICS. Sep 2017. 44(9):423-437.

24. Chen, Jia*; Miller, Brendan F.; Furano, Anthony V.^#; .Repair of naturally occurring mismatches can induce mutations in flanking DNA.ELIFE. 2014. 3.

25. Hu, Guang-Jing*; Chen, Jia*; Zhao, Xiao-Nan*; Xu, Jia-Jia; Guo, Dong-Qing; Lu, Ming; Zhu, Ming; Xiong, Ying; Li, Qin; Chang, Catherine C. Y.; Song, Bao-Liang; Chang, Ta-Yuan; Li, Bo-Liang^#; .Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene.CELL RESEARCH. 2013. 23(8):1007-1024.

26. Chen, Jia*; Zhao, Xiao-Nan*; Yang, Li; Hu, Guang-Jing; Lu, Ming; Xiong, Ying; Yang, Xin-Ying; Chang, Catherine C. Y.; Song, Bao-Liang; Chang, Ta-Yuan; Li, Bo-Liang^#; .RNA secondary structures located in the interchromosomal region of human ACAT1 chimeric mRNA are required to produce the 56-kDa isoform.CELL RESEARCH. 2008. 18(9):921-936.