王皞鹏

1. Li, Wentao*; Qiu, Shizhen; Chen, Jian; Jiang, Shutan; Chen, Wendong; Jiang, Jingwei; Wang, Fei; Si, Wen; Shu, Yilai; Wei, Ping; Fan, Gaofeng; Tian, Ruijun; Wu, Haitao^#; Xu, Chenqi^#; Wang, Haopeng^#.Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy.IMMUNITY. 18 Aug 2020. 53(2):456-+.

2. Wang, Yuetong*; Wang, Fei*; Wang, Lihua*; Qiu, Shizhen*; Yao, Yufeng; Yan, Chenxu; Xiong, Xuexue; Chen, Xuyong; Ji, Quanquan; Cao, Jian; Gao, Ganglong; Li, Dake; Zhang, Liye; Guo, Zhiqian; Wang, Ruoning; Wang, Haopeng^#; Fan, Gaofeng^#.NAD(+) supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells.CELL REPORTS. 2021. 36(6).

3. Wang, Haopeng^#*; Song, Xianming; Shen, Lianjun; Wang, Xinxin; Xu, Chenqi^#.Exploiting T cell signaling to optimize engineered T cell therapies.TRENDS IN CANCER. Feb 2022. 8(2).

4. Chen, Jian*; Qiu, Shizhen; Li, Wentao; Wang, Kun; Zhang, Yu; Yang, Han; Liu, Baichuan; Li, Guangfei; Li, Li; Chen, Min; Lan, Junjie; Niu, Jiahua; He, Peijie; Cheng, Lei; Fan, Gaofeng; Liu, Xin; Song, Xianmin^#; Xu, Chenqi^#; Wu, Haitao^#; Wang, Haopeng^#.Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness.CELL RESEARCH;. 2023.

5. Liu, Qiang*; Zheng, Jun; Sun, Weiping; Huo, Yinbo; Zhang, Liye; Hao, Piliang; Wang, Haopeng^#; Zhuang, Min^#.A proximity-tagging system to identify membrane protein-protein interactions.NATURE METHODS. Sep 2018. 15(9):715-+.

6. Wu, Wei*; Zhou, Qiuping; Masubuchi, Takeya; Shi, Xiaoshan; Li, Hua; Xu, Xinyi; Huang, Min; Meng, Li; He, Xing; Zhu, Hengyu; Gao, Shuaixin; Zhang, Nan; Jing, Ruirui; Sun, Jie; Wang, Haopeng; Hui, Enfu^#; Wong, Catherine Chiulan^#; Xu, Chenqi^#.Multiple Signaling Roles of CD3 epsilon and Its Application in CAR-T Cell Therapy.CELL. 20 Aug 2020. 182(4):855-+.

7. Shang, Wanjing*; Jiang, Yong*; Boettcher, Michael; Ding, Kang; Mollenauer, Marianne; Liu, Zhongyi; Wen, Xiaofeng; Liu, Chang; Hao, Piliang; Zhao, Suwen; McManus, Michael T.; Wei, Lai^#; Weiss, Arthur^#; Wang, Haopeng^#.Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 24 Apr 2018. 115(17):E4051-E4060.

8. Shang, Wanjing*; Wang, Fei*; Fan, Gaofeng^#; Wang, Haopeng^#.Key elements for designing and performing a CRISPR/Cas9-based genetic screen.JOURNAL OF GENETICS AND GENOMICS. 20 Sep 2017. 44(9):439-449.

9. Yongqin Li*; Yuxin Chen*; Shaoshuai Mao*; Ravinder Kaunda; Zhengyu Jing; Qin Chen; Xinxin Wang; Jing Xia; Dahai Liu; Jianlong Sun; Haopeng Wang; Tian Chi^#.In situ conversion of defective Treg into SuperTreg cells to treat advanced IPEX-like disorders in mice.NATURE COMMUNICATIONS. 03 Jun 2020. 11:2781.

10. Xu, Xiaozheng*; Hou, Bowen; Fulzele, Amitkumar; Masubuchi, Takeya; Zhao, Yunlong; Wu, Zijun; Hu, Yanyan; Jiang, Yong; Ma, Yanzhe; Wang, Haopeng; Bennett, Eric J.; Fu, Guo^#; Hui, Enfu^#.PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.JOURNAL OF CELL BIOLOGY. 01 Jun 2020. 219(6).

11. Yang, Wei*; Pan, Weiling; Chen, Shuokai; Trendel, Nicola; Jiang, Shutan; Xiao, Feng; Xue, Manman; Wu, Wei; Peng, Zeli; Li, Xiaoxi; Ji, Hongbin; Liu, Xiaolong; Jiang, Hai; Wang, Haopeng; Shen, Hongbin; Dushek, Omer^#; Li, Hua^#; Xu, Chenqi^#.Dynamic regulation of CD28 conformation and signaling by charged lipids and ions.NATURE STRUCTURAL & MOLECULAR BIOLOGY. Dec 2017. 24(12):1081-+.

12. Li, Lunyi*; Guo, Xingdong; Shi, Xiaoshan; Li, Changting; Wu, Wei; Yan, Chengsong; Wang, Haopeng; Li, Hua; Xu, Chenqi^#.Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 18 Jul 2017. 114(29):E5891-E5899.

13. Chi, Shen*; Weiss, Arthur^#; Wang, Haopeng^#.A CRISPR-Based Toolbox for Studying T Cell Signal Transduction.BIOMED RESEARCH INTERNATIONAL. 2016.

14. Liu, Wanli^#*; Wang, Haopeng; Xu, Chenqi^#.Antigen Receptor Nanoclusters: Small Units with Big Functions.TRENDS IN IMMUNOLOGY. Oct 2016. 37(10):680-689.

15. Tian, Ruijun^#*; Wang, Haopeng*; Gish, Gerald D.; Petsalaki, Evangelia; Pasculescu, Adrian; Shi, Yu; Mollenauer, Marianne; Bagshaw, Richard D.; Yosef, Nir; Hunter, Tony; Gingras, Anne-Claude; Weiss, Arthur^#; Pawson, Tony.Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015. 112(13):E1594-E1603.

16. Punwani, Divya*; Wang, Haopeng*; Chan, Alice Y.; Cowan, Morton J.; Mallott, Jacob; Sunderam, Uma; Mollenauer, Marianne; Srinivasan, Rajgopal; Brenner, Steven E.; Mulder, Arend; Claas, Frans H. J.; Weiss, Arthur; Puck, Jennifer M.^#.Combined Immunodeficiency Due to MALT1 Mutations, Treated by Hematopoietic Cell Transplantation.JOURNAL OF CLINICAL IMMUNOLOGY. 2015. 35(2):135-146.

17. Wang, Haopeng*; Flach, Henrik; Onizawa, Michio; Wei, Lai; McManus, Michael T.; Weiss, Arthur^#.Negative regulation of Hif1a expression and T(H)17 differentiation by the hypoxia-regulated microRNA miR-210.NATURE IMMUNOLOGY. 2014. 15(4):393+.

18. Zhuang, Min*; Guan, Shenheng; Wang, Haopeng; Budingame, Alma L.; Wells, James A.^#.Substrates of IAP Ubiquitin Ligases Identified with a Designed Orthogonal E3 Ligase, the NEDDylator.MOLECULAR CELL. 2013. 49(2):273-282.

19. Wang, Haopeng*; Kadlecek, Theresa A.; Au-Yeung, Byron B.; Goodfellow, Hanna E. Sjoelin; Hsu, Lih-Yun; Freedman, Tanya S.; Weiss, Arthur^#.ZAP-70: An Essential Kinase in T-cell Signaling.COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2010. 2(5).

20. Wang, Haopeng*; Holst, Jeff; Woo, Seng-Ryong; Guy, Cliff; Bettini, Matt; Wang, Yao; Shafer, Aaron; Naramura, Mayumi; Mingueneau, Michael; Dragone, Leonard L.; Hayes, Sandra M.; Malissen, Bernard; Band, Hamid; Vignali, Dario A. A.^#.Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development.EMBO JOURNAL. 2010. 29(7):1285-1298.

21. Wang, Haopeng*; Matsuzawa, Atsushi; Brown, Scott A.; Zhou, JingRan; Guy, Cliff S.; Tseng, Ping-Hui; Forbes, Karen; Nicholson, Thomas P.; Sheppard, Paul W.; Hacker, Hans; Karin, Michael^#; Vignali, Dario A. A.^#.Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008. 105(51):20197-20202.

22. Vallabhapurapu, Sivakumar*; Matsuzawa, Atsushi; Zhang, WeiZhou; Tseng, Ping-Hui; Keats, Jonathan J.; Wang, Haopeng; Vignali, Dario A. A.; Bergsagel, P. Leif; Karin, Michael^#.Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappa B signaling.NATURE IMMUNOLOGY. 2008. 9(12):1364-1370.

23. Holst, Jeff*; Wang, Haopeng; Eder, Kelly Durick; Workman, Creg J.; Boyd, Kelli L.; Baquet, Zachary; Singh, Harvir; Forbes, Karen; Chruscinski, Andrzej; Smeyne, Richard; van Oers, Nicolai S. C.; Utz, Paul J.; Vignali, Dario A. A.^#.Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity.NATURE IMMUNOLOGY. 2008. 9(6):658-666.

24. Matsuzawa, Atsushi*; Tseng, Ping-Hui; Vallabhapurapu, Sivakumar; Luo, Jun-Li; Zhang, Weizhou; Wang, Haopeng; Vignali, Dario A. A.; Gallagher, Ewen; Karin, Michael^#.Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex.SCIENCE. 2008. 321(5889):663-668.