Pengfei Paul Lu

1. Rongze Ma^#*; Difei Gong; Huanyang You; Yunzhe Lu; Bergers Gabriel; Zena Werb; Ophir Klein; Pengfei Lu.LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland..CELL REPORTS. 15 Feb 2022. 38(7):110375.

2. Yunzhe Lu^#*; Tao Zhou; Chongshen Xu; Xu Wang; Yu Kong*; Guohong Hu; Xiangying Kong*; Pengfei Lu.Occludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR.PLOS BIOLOGY. 18 Jan 2022.

3. Yunzhe Lu^#*; Ruolan Deng^#; Huanyang You; Pengfei Lu.3D in vitro culture system to study collective migration in mammary organoid epithelium..STAR PROTOCOL. 27 Aug 2021.

4. Lu, Pengfei^#*; Lu, Yunzhe.Born to Run? Diverse Modes of Epithelial Migration.FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021. 9.

5. Yunzhe Lu^#*; Ruolan Deng; Huanyang You; Yishu Xu; Christopher Antos; Jianglong Sun; Ophir Klein; Pengfei Lu.Asymmetric Stratification-Induced Polarity Loss and Coordinated Individual Cell Movements Drive Directional Migration of Vertebrate Epithelium..CELL REPORTS. 13 Oct 2020.

6. Littlepage, Laurie E.^#*; Ewald, Andrew J.; Alexander, Caroline; Casbon, Amy-Jo; Lu, Pengfei; Kessenbrock, Kai; Provot, Sylvain; Phillips, Joanna J.; Kouros-Mehr, Hosein; Chan, Matilda; Welm, Bryan; Lilla, Jennifer N.; Chou, Jonathan; Lawson, Devon; Lemieux, George; Plaks, Vicki; Egeblad, Mikala; Sternlicht, Mark.Obituary Zena Werb (1945-2020).CELL STEM CELL. 03 Sep 2020. 27(3):356-358.

7. Zhang Ziheng*; Sun Weiping*; Shi Tiezhu*; Lu Pengfei^#; Zhuang Min^#; Liu Ji-Long^#.Capturing RNA-protein Interaction via CRUIS.NUCLEIC ACIDS RESEARCH. 06 Mar 2020. 48(9):e52.

8. Zhou, Tao*; Lu, Yunzhe*; Xu, Chongshen*; Wang, Rui; Zhang, Liye; Lu, Pengfei^#.Occludin protects secretory cells from ER stress by facilitating SNARE-dependent apical protein exocytosis.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 03 Mar 2020. 117(9):4758-4769.

9. Shi, Tiezhu*; Yao, Linli; Han, Ying; Hao, Piliang; Lu, Pengfei^#.Quantitative Phosphoproteomics Reveals System-Wide Phosphorylation Network Altered by Spry in Mouse Mammary Stromal Fibroblasts.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Nov 2019. 20(21).

10. Lu, Pengfei^#*; Zhou, Tao; Xu, Chongshen; Lu, Yunzhe.Mammary stem cells, where art thou?.WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY. 19 Jul 2019.

11. Koledova Zuzana*, Lu Pengfei, Martin F, Stein T, Howlin J.A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland.MAMMARY GLAND DEVELOPMENT: METHODS AND PROTOCOLS. 2017. 1501:217-231.

12. Yao, Linli*; Lu, Pengfei; Ling, Eng-Ang^#.Melatonin Suppresses Toll Like Receptor 4-Dependent Caspase-3 Signaling Activation Coupled with Reduced Production of Proinflammatory Mediators in Hypoxic Microglia.PLOS ONE. 03 Nov 2016. 11(11).

13. Koledova, Zuzana*; Zhang, Xiaohong; Streuli, Charles; Clarke, Robert B.; Klein, Ophir D.; Werb, Zena^#; Lu, Pengfei^#.SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 27 Sep 2016. 113(39):E5731-E5740.

14. Zhang, Xiaohong*; Martinez, Denisse; Koledova, Zuzana; Qiao, Guijuan; Streuli, Charles H.; Lu, Pengfei^#.FGF ligands of the postnatal mammary stroma regulate distinct aspects of epithelial morphogenesis.DEVELOPMENT. 2014. 141(17):3352-3362.

15. Lu, Pengfei*; Takai, Ken; Weaver, Valerie M.; Werb, Zena^#.Extracellular Matrix Degradation and Remodeling in Development and Disease.COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2011. 3(12).

16. Lu, Pengfei*; Werb, Zena^#.Patterning Mechanisms of Branched Organs.SCIENCE. 2008. 322(5907):1506-1509.

17. Lu, Pengfei*; Ewald, Andrew J.; Martin, Gail R.; Werb, Zena^#.Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis.DEVELOPMENTAL BIOLOGY. 2008. 321(1):77-87.

18. Lu, Pengfei^#*; Yu, Ying; Perdue, Yasmine; Werb, Zena^#.The apical ectodermal ridge is a timer for generating distal limb progenitors.DEVELOPMENT. 2008. 135(8):1395-1405.

19. Lu, PF*; Minowada, G; Martin, GR^#.Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function.DEVELOPMENT. 2006. 133(1):33-42.

20. Werb, Zena^#*; Lu, Pengfei.The Role of Stroma in Tumor Development.CANCER JOURNAL. 01 Jul 2015. 21(4):250-253.

21. Lu, Pengfei*; Sternlicht, Mark D.; Werb, Zena^#.Comparative mechanisms of branching morphogenesis in diverse systems.JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA. 2006. 11(2020-03-04):213-228.

22. Sternlicht, Mark D.^#*; Kouros-Mehr, Hosein; Lu, Pengfei; Werb, Zena.Hormonal and local control of mammary branching morphogenesis.DIFFERENTIATION. 2006. 74(7):365-381.

23. Lu, Pengfei*; Weaver, Valerie M.; Werb, Zena^#.The extracellular matrix: A dynamic niche in cancer progression.JOURNAL OF CELL BIOLOGY. 2012. 196(4):395-406.

24. Zhang Xiaohong*; Qiao Guijuan; Lu Pengfei^#.Modulation of Fibroblast Growth Factor Signaling Is Essential for Mammary Epithelial Morphogenesis.PLOS ONE. 09 Apr 2014. 9(4):e92735.

25. Kim, Eun-Jung*; Jung, Han-Sung^#; Lu, Pengfei^#.Pleiotropic Functions of Fibroblast Growth Factor Signaling in Embryonic Mammary Gland Development.J MAMMARY GLAND BIOL NEOPLASIA. 24 Apr 2013. 18:139-142.

26. Howard, Beatrice A.^#*; Lu, Pengfei^#.Stromal regulation of embryonic and postnatal mammary epithelial development and differentiation.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 2014. 25:43-51.