徐菲
发布者：人员机构发布时间：2023-12-01浏览次数：102
- 1. Heng Liu*, You Zheng*, Yue Wang*, Yumeng Wang*, Xinheng He, Peiyu Xu, Sijie Huang, Qingning Yuan, Xinyue Zhang, Ling Wang, Kexin Jiang, Hong Chen, Zhen Li, Wenbin Liu##, Sheng Wang##, H. Eric Xu##, Fei Xu##.Recognition of methamphetamine and other amines by trace amine receptor TAAR1.Nature. Nov 2023.
- 2. Li, Cuixia*; Wu, Yiran; Wang, Wenli; Xu, Lu; Zhou, Yan; Yue, Yang; Wu, Tingting; Yang, Meifang; Qiu, Yanli; Huang, Minhao; Zhou, Fangfang; Zhou, Yiqing; Hao, Piliang; Lin, Zhixiong; Wang, Ming-Wei; Zhao, Suwen#; Yang, Dehua#; Xu, Fei#; Tao, Houchao#; .Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7.JOURNAL OF MEDICINAL CHEMISTRY. 05 Sep 2023.
- 3. Lin, Xi*; Jiang, Shan*; Wu, Yiran; Wei, Xiaohu; Han, Gye-Won; Wu, Lijie; Liu, Junlin; Chen, Bo; Zhang, Zhibin; Zhao, Suwen; Cherezov, Vadim; Xu, Fei#.The activation mechanism and antibody binding mode for orphan GPR20.CELL DISCOVERY;. 01 Dec 2023. 9(1).
- 4. Lin Xi*, Chen B*, Wu Y*, Han Y, Qi A, Wang J, Yang Z, Wei X, Zhao T, Wu L, Xie X, Sun J, Zheng J#, Zhao S#, Xu F#.Cryo-EM structures of orphan GPR21 signaling complexes.Nature Communications. Jan 2023.
- 5. Yue, Yang*; Liu, Lier*; Wu, Li-Jie*; Wu, Yiran; Wang, Ling; Li, Fei; Liu, Junlin; Han, Gye-Won; Chen, Bo; Lin, Xi; Brouillette, Rebecca L.; Breault, Emile; Longpre, Jean-Michel; Shi, Songting; Lei, Hui; Sarret, Philippe; Stevens, Raymond C.; Hanson, Michael A.; Xu, Fei#.Structural insight into apelin receptor-G protein stoichiometry.NATURE STRUCTURAL & MOLECULAR BIOLOGY. Jul 2022. 29(7).
- 6. Chen Yuxiang*, Chen B*, Wu T*, Zhou F, Xu F#.Cryo-EM structure of human κ-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A.Protein & Cell. Aug 2022.
- 7. Zheng, You*; Liu, Heng; Chen, Yuxin; Dong, Shaowei; Wang, Fang; Wang, Shengyi; Li, Geng-Lin; Shu, Yilai#; Xu, Fei#.Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel.NEURON. 19 Jan 2022. 110(2).
- 8. Xu, Lu*; Chen, Bo; Schihada, Hannes; Wright, Shane C.; Turku, Ainoleena; Wu, Yiran; Han, Gye-Won; Kowalski-Jahn, Maria; Kozielewicz, Pawel; Bowin, Carl-Fredrik; Zhang, Xianjun; Li, Chao; Bouvier, Michel; Schulte, Gunnar#; Xu, Fei#.Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G(s).CELL RESEARCH. Dec 2021.
- 9. Lin, Xi*; Li, Mingyue*; Wang, Niandong*; Wu, Yiran*; Luo, Zhipu; Guo, Shimeng; Han, Gye-Won; Li, Shaobai; Yue, Yang; Wei, Xiaohu; Xie, Xin; Chen, Yong; Zhao, Suwen; Wu, Jian#; Lei, Ming#; Xu, Fei#.Structural basis of ligand recognition and self-activation of orphan GPR52.NATURE. 19 Feb 2020.
- 10. Yang, Shifan*; Wu, Yiran; Xu, Ting-Hai; de Waal, Parker W.; He, Yuanzheng; Pu, Mengchen; Chen, Yuxiang; DeBruine, Zachary J.; Zhang, Bingjie; Zaidi, Saheem A.; Popov, Petr; Guo, Yu; Han, Gye Won; Lu, Yang; Suino-Powell, Kelly; Dong, Shaowei; Harikumar, Kaleeckal G.; Miller, Laurence J.; Katritch, Vsevolod; Xu, H. Eric; Shui, Wenqing; Stevens, Raymond C.; Melcher, Karsten; Zhao, Suwen; Xu, Fei#.Crystal structure of the Frizzled 4 receptor in a ligand-free state.NATURE. 2018. 560(7720):666-670.
- 11. Zhang, Xianjun*; Zhao, Fei; Wu, Yiran; Yang, Jun; Han, Gye Won; Zhao, Suwen; Ishchenko, Andrii; Ye, Lintao; Lin, Xi; Ding, Kang; Dharmarajan, Venkatasubramanian; Griffin, Patrick R.; Gati, Cornelius; Nelson, Garrett; Hunter, Mark S.; Hanson, Michael A.; Cherezov, Vadim; Stevens, Raymond C.; Tan, Wenfu#; Tao, Houchao#; Xu, Fei#.Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.NATURE COMMUNICATIONS. 17 May 2017. 8(1).
- 12. Zhang, Xianjun*; Dong, Shaowei; Xu, Fei#.Structural and Druggability Landscape of Frizzled G Protein-Coupled Receptors.TRENDS IN BIOCHEMICAL SCIENCES. Dec 2018. 43(12):1033-1046.
- 13. Xu, Fei*; Wu, Huixian; Katritch, Vsevolod; Han, Gye Won; Jacobson, Kenneth A.; Gao, Zhan-Guo; Cherezov, Vadim; Stevens, Raymond C.#.Structure of an Agonist-Bound Human A(2A) Adenosine Receptor.SCIENCE. 2011. 332(6027):322-327.
- 14. Zhang, Xianjun*; Stevens, Raymond C.; Xu, Fei#.The importance of ligands for G protein-coupled receptor stability.TRENDS IN BIOCHEMICAL SCIENCES. Feb 2015. 40(2):79-87.
- 15. Ma, Yingli*; Yue, Yang; Ma, Yanbin; Zhang, Qing; Zhou, Qingtong; Song, Yunpeng; Shen, Yuqing; Li, Xun; Ma, Xiaochuan; Li, Chao; Hanson, Michael A.; Han, Gye Won; Sickmier, E. Allen; Swaminath, Gayathri; Zhao, Suwen; Stevens, Raymond C.; Hu, Liaoyuan A.; Zhong, Wenge; Zhang, Mingqiang; Xu, Fei#.Structural Basis for Apelin Control of the Human Apelin Receptor.STRUCTURE. 06 Jun 2017. 25(6):858-+.
- 16. Xu, Fei*; Liu, Wei; Hanson, Michael A.; Stevens, Raymond C.; Cherezov, Vadim#.Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases.CRYSTAL GROWTH & DESIGN. 2011. 11(4):1193-1201.
- 17. Xu, Fei*; Stevens, Raymond C.#.Trapping Small Caffeine in a Large GPCR Pocket.STRUCTURE. 2011. 19(9):1204-1207.
- 18. Liu, Wei*; Chun, Eugene; Thompson, Aaron A.; Chubukov, Pavel; Xu, Fei; Katritch, Vsevolod; Han, Gye Won; Roth, Christopher B.; Heitman, Laura H.; IJzerman, Adriaan P.; Cherezov, Vadim#; Stevens, Raymond C.#.Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions.SCIENCE. 2012. 337(6091):232-236.
- 19. Chun, Eugene*; Thompson, Aaron A.; Liu, Wei; Roth, Christopher B.; Griffith, Mark T.; Katritch, Vsevolod; Kunken, Joshua; Xu, Fei; Cherezov, Vadim; Hanson, Michael A.#; Stevens, Raymond C.#.Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors.STRUCTURE. 2012. 20(6):967-976.
- 20. Tosh, Dilip K.*; Phan, Khai; Gao, Zhan-Guo; Gakh, Andrei A.; Xu, Fei; Deflorian, Francesca; Abagyan, Ruben; Stevens, Raymond C.; Jacobson, Kenneth A.#; Katritch, Vsevolod#.Optimization of Adenosine 5 '-Carboxamide Derivatives as Adenosine Receptor Agonists Using Structure-Based Ligand Design and Fragment Screening.JOURNAL OF MEDICINAL CHEMISTRY. 2012. 55(9):4297-4308.
- 21. Deflorian, Francesca*; Kumar, T. Santhosh; Phan, Khai; Gao, Zhan-Guo; Xu, Fei; Wu, Huixian; Katritch, Vsevolod; Stevens, Raymond C.; Jacobson, Kenneth A.#.Evaluation of Molecular Modeling of Agonist Binding in Light of the Crystallographic Structure of an Agonist-Bound A(2A) Adenosine Receptor.JOURNAL OF MEDICINAL CHEMISTRY. 2012. 55(1):538-552.
- 22. Xue, Dongxiang*; Ye, Lintao; Zheng, Jun; Wu, Yiran; Zhang, Xianjun; Xu, Yueming; Li, Tao; Stevens, Raymond C.; Xu, Fei; Zhuang, Min; Zhao, Suwen; Zhao, Fei#; Tao, Houchao#.The structure-based traceless specific fluorescence labeling of the smoothened receptor.ORGANIC & BIOMOLECULAR CHEMISTRY. 07 Jul 2019. 17(25):6136-6142.
- 23. Ye, Lintao*; Ding, Kang; Zhao, Fei; Liu, Xiaoyan; Wu, Yiran; Liu, Yang; Xue, Dongxiang; Zhou, Fang; Zhang, Xianjun; Stevens, Raymond C.; Xu, Fei; Zhao, Suwen#; Tao, Houchao#.A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor.MEDCHEMCOMM. Jun 2017. 8(6):1332-1336.
- 24. Zhao, Huan*; Tian, Xueying; He, Lingjuan; Li, Yan; Pu, Wenjuan; Liu, Qiaozhen; Tang, Juan; Wu, Jiaying; Cheng, Xin; Liu, Yang; Zhou, Qingtong; Tan, Zhen; Bai, Fan; Xu, Fei; Smart, Nicola; Zhou, Bin#.Apj(+) Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target.CELL REPORTS. 30 Oct 2018. 25(5):1241-+.
- 25. Zhou, F.*; Ding, K.; Zhou, Y.; Liu, Y.; Liu, X.; Zhao, F.; Wu, Y.; Zhang, X.; Xu, F.; Zhao, S.; Tao, H..Determination of an underneath binding in the transmembrane domain of smoothened receptor.JOURNAL OF BIOENERGETICS AND BIOMEMBRANES. Dec 2018. 50(6):510-510.
- 26. Lin, X.*; Xu, F..Toward the first orphan GPCR structure.JOURNAL OF BIOENERGETICS AND BIOMEMBRANES. Dec 2018. 50(6):559-559.
- 27. Zhou, Fang*; Ding, Kang; Zhou, Yiqing; Liu, Yang; Liu, Xiaoyan; Zhao, Fei; Wu, Yiran; Zhang, Xianjun; Tan, Qiwen; Xu, Fei; Tan, Wenfu; Xiao, Youli#; Zhao, Suwen#; Tao, Houchao#.Colocalization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor.JOURNAL OF MEDICINAL CHEMISTRY. 14 Nov 2019. 62(21):9983-9989.
- 28. Lin, Xi*; Chen, Bo; Wu, Yiran; Han, Yingqi; Qi, Ao; Wang, Junyan; Yang, Zhao; Wei, Xiaohu; Zhao, Tingting; Wu, Lijie; Xie, Xin; Sun, Jinpeng; Zheng, Jie#; Zhao, Suwen#; Xu, Fei#.Cryo-EM structures of orphan GPR21 signaling complexes.NATURE COMMUNICATIONS;. 01 Dec 2023. 14(1).
