程建军

1. Chen, Zhangcheng*; Yu, Jing; Wang, Huan; Xu, Peiyu; Fan, Luyu; Sun, Fengxiu; Huang, Sijie; Zhang, Pei; Huang, He; Gu, Shuo; Zhang, Bowen; Zhou, Yue; Wan, Xiaobo; Pei, Gang; Xu, H. Eric^#; Cheng, Jianjun^#; Wang, Sheng^#; .Flexible scaffold-based cheminformatics approach for polypharmacological drug design.CELL. 25 Apr 2024. 187(9).

2. Duan, Wenwen*; Cao, Dongmei; Wang, Sheng^#; Cheng, Jianjun^#; .Serotonin 2A Receptor (5-HT2AR) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants.CHEMICAL REVIEWS. 2023. 124(1):124-163.

3. Liu, Ruiquan*; Duan, Wenwen; Yan, Wenzhong; Zhang, Jinfeng; Cheng, Jianjun^#; .Design and synthesis of tri-substituted pyrimidine derivatives as bifunctional tumor immunotherapeutic agents targeting both A 2A adenosine receptors and histone deacetylases.CHINESE CHEMICAL LETTERS. 2024. 35(1).

4. Li, Huiqiong*; Cheng, Jianjun^#.2-Phenylcyclopropylmethylamine (PCPMA) as a privileged scaffold for central nervous system drug design.BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. 2024. 101: 129654.

5. Jianhang Mao*; Yilong Cui; Huan Wang; Wenwen Duan; Zhi-Jie Liu; Tian Hua*; Ning Zhou^#; Jianjun Cheng^#; .Design and Synthesis of Novel GPR139 Agonists with Therapeutic Effects in Mouse Models of Social Interaction and Cognitive Impairment.JOURNAL OF MEDICINAL CHEMISTRY. 13 Oct 2023. 66(20):14011–14028.

6. Liu, Ruiquan*; Qi, Jianzhong; Wang, Huan; Fan, Luyu; Zhang, Pei; Yu, Jing; Tan, Liang; Wang, Sheng^#; Cheng, Jianjun^#; .Transformation of a Dopamine D2 Receptor Agonist to Partial Agonists as Novel Antipsychotic Agents.JOURNAL OF MEDICINAL CHEMISTRY. 11 May 2023. 66(9).

7. Sun, Nan*; Yang, Kexin*; Yan, Wenzhong; Yao, Mingyue; Xie, Chengying^#; Cheng, Jianjun^#; Yu, Chengcheng; Duan, Wenwen; Gu, Xiaoke; Guo, Dong; Jiang, Hualiang; .Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response.JOURNAL OF MEDICINAL CHEMISTRY. 01 Mar 2023.

8. Zhang, Jinfeng*; Feng, Dandan; Cheng, Jianjun^#; Wüthrich, Kurt^#; .Adenosine A2AReceptor (A2AAR) Ligand Screening Using the 19F-NMR Probe FPPA.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2023. 145(28):15061-15064.

9. Cao, Dongmei*; Yu, Jing; Wang, Huan; Luo, Zhipu; Liu, Xinyu; He, Licong; Qi, Jianzhong; Fan, Luyu; Tang, Lingjie; Chen, Zhangcheng; Li, Jinsong; Cheng, Jianjun^#; Wang, Sheng^#; .Structure-based discovery of nonhallucinogenic psychedelic analogs.SCIENCE. 28 Jan 2022. 375(6579).

10. Chen, Zhangcheng*; Fan, Luyu; Wang, Huan; Yu, Jing; Lu, Dengyu; Qi, Jianzhong; Nie, Fen; Luo, Zhipu; Liu, Zhen; Cheng, Jianjun^#; Wang, Sheng^#; .Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties.NATURE NEUROSCIENCE. Jan 2022.

11. Wang, Jingjing*; Wu, Meng; Chen, Zhangcheng; Wu, Lijie; Wang, Tian; Cao, Dongmei; Wang, Huan; Liu, Shenhui; Xu, Yueming; Li, Fei; Liu, Junlin; Chen, Na; Zhao, Suwen; Cheng, Jianjun^#; Wang, Sheng^#; Hua, Tian^#; .The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands.NATURE COMMUNICATIONS. 23 May 2022. 13(1).

12. Gu, Xiaoke*; Yuan, Haoxing; Zhao, Wenchao; Sun, Nan; Yan, Wenzhong; Jiang, Chunyu; He, Yan; Liu, Hongli; Cheng, Jianjun^#; Guo, Dong^#; .Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V2 Receptor in In Vitro, Ex Vivo, and In Vivo Models of ADPKD.JOURNAL OF MEDICINAL CHEMISTRY. 01 Dec 2022. 66(2).

13. Zhang, Jinfeng*; Luo, Ziwei; Duan, Wenwen; Yang, Kexin; Ling, Lijun; Yan, Wenzhong; Liu, Ruiquan; Wuthrich, Kurt; Jiang, Hualiang^#; Xie, Chengying^#; Cheng, Jianjun^#; .Dual-acting antitumor agents targeting the A 2A adenosine receptor and histone deacetylases: Design and synthesis of 4-(furan-2-yl)-1H- pyrazolo[3,4-d]pyrimidin-6-amine derivatives.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 05 Jun 2022. 5(236):1-14.

14. Zhang, Haoran*; Yan, Wenzhong; Sun, Yongzhan; Yuan, Haoxing; Su, Limin; Cao, Xudong; Wang, Peng; Xu, Zhou; Hu, Youhui; Wang, Zhongjian; Wang, Yinan; Fu, Kequan; Sun, Ying; Chen, Yupeng^#; Cheng, Jianjun^#; Guo, Dong^#; .Long Residence Time at the Vasopressin V-2 Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease.JOURNAL OF MEDICINAL CHEMISTRY. 09 Jun 2022. 65(11).

15. Yan, Wenzhong*; Ling, Lijun; Wu, Yiran; Yang, Kexin; Liu, Ruiquan; Zhang, Jinfeng; Zhao, Simeng; Zhong, Guisheng; Zhao, Suwen; Jiang, Hualiang^#; Xie, Chengying^#; Cheng, Jianjun^#; .Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A(2A) Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents.JOURNAL OF MEDICINAL CHEMISTRY. 25 Nov 2021. 64(22).

16. Yan, Wenzhong*; Fan, Luyu; Yu, Jing; Liu, Ruiquan; Wang, Huan; Tan, Liang; Wang, Sheng^#; Cheng, Jianjun^#; .2-Phenylcyclopropylmethylamine Derivatives as Dopamine D-2 Receptor Partial Agonists: Design, Synthesis, and Biological Evaluation.JOURNAL OF MEDICINAL CHEMISTRY. 09 Dec 2021. 64(23).

17. Duan, Wenwen*; Sun, Ying; Wu, Meng; Zhang, Zhiyuan; Zhang, Taotao; Wang, Huan; Li, Fei; Yang, Lingyun; Xu, Yueming; Liu, Zhi-Jie; Hua, Tian^#; Nie, Hong^#; Cheng, Jianjun^#; .Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 15 Dec 2021. 226.

18. Chan, H. C. Stephen*; Xu, Yueming; Tan, Liang; Vogel, Horst; Cheng, Jianjun^#; Wu, Dong^#; Yuan, Shuguang^#; .Enhancing the Signaling of GPCRs via Orthosteric Ions.ACS CENTRAL SCIENCE. 26 Feb 2020. 6(2):274-282.

19. Fan, Luyu*; Tan, Liang; Chen, Zhangcheng; Qi, Jianzhong; Nie, Fen; Luo, Zhipu; Cheng, Jianjun^#; Wang, Sheng^#; .Haloperidol bound D-2 dopamine receptor structure inspired the discovery of subtype selective ligands.NATURE COMMUNICATIONS. 26 Feb 2020. 11(1).

20. Zhang, Jinfeng*; Yan, Wenzhong; Duan, Wenwen; Wuthrich, Kurt; Cheng, Jianjun^#; .Tumor Immunotherapy Using A(2A) Adenosine Receptor Antagonists.PHARMACEUTICALS. Sep 2020. 13(9).

21. Tan, Liang*; Zhou, Qingtong; Yan, Wenzhong; Sun, Jian; Kozikowski, Alan P.; Zhao, Suwen; Huang, Xi-Ping^#; Cheng, Jianjun^#; .Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands.JOURNAL OF MEDICINAL CHEMISTRY. 14 May 2020. 63(9):4579-4602.

22. Tan, Liang*; Yan, Wenzhong; McCorvy, John D.^#; Cheng, Jianjun^#; .Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential.JOURNAL OF MEDICINAL CHEMISTRY. 22 Nov 2018. 61(22):9841-9878.

23. Duan, Wenwen*; Cao, Dongmei; Wang, Wang, Sheng^#; Cheng, Jianjun^#.Serotonin 2A Receptor (5-HT2AR) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants.CHEMICAL REVIEWS. 2024. 124(1): 124-163.