Kaixian Chen, PhDDistinguished Adjunct Professor from CAS

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Email: kxchen@@simm.ac.cn

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Principal investigator

Name:

Kaixian ChenDistinguished Adjunct Professor from CAS , PhD, Distinguished Adjunct Professor from CAS

Position:

Affiliation:

School of Life Science and Technology, ShanghaiTech / Shanghai Institute of Materia Medica, CAS

Honor:

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Working Experience:

Group Introduction

Research Area:

Drug Discovery and Drug Design

Research Interests:

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Research Achievement

Representative Publications (*First Author, # Corresponding Author)

1. Xu, YC*; Shen, JH^#; Luo, XM; Silman, I; Sussman, JL; Chen, KX; Jiang, HL.How does Huperzine A enter and leave the binding gorge of acetylcholinesterase? Steered molecular dynamics simulations.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2003. 125(37):11340-11349.
2. Xu, YC*; Shen, JJ; Luo, XM; Zhu, WL; Chen, KX; Ma, JP^#; Jiang, HL.Conformational transition of amyloid beta-peptide.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005. 102(15):5403-5407.
3. Zhang, Jian*; Lu, Chenjing; Chen, Kaixian; Zhu, Weiliang; Shen, Xu; Jiang, Hualiang^#.Conformational transition pathway in the allosteric process of human glucokinase.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006. 103(36):13368-13373.
4. Shen, Juwen*; Zhang, Jian; Luo, Xiaomin; Zhu, Weiliang; Yu, Kunqian; Chen, Kaixian; Li, Yixue; Jiang, Hualiang^#.Predictina protein-protein interactions based only on sequences information.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007. 104(11):4337-4341.
5. Feng, Yu*; Ding, Xiao; Chen, Tao; Chen, Lili; Liu, Fang; Jia, Xu; Luo, Xiaomin; Shen, Xu; Chen, Kaixian; Jiang, Hualiang; Wang, Hui^#; Liu, Hong; Liu, Dongxiang.Design, Synthesis, and Interaction Study of Quinazoline-2(1H)-thione Derivatives as Novel Potential Bcl-x(L) Inhibitors.JOURNAL OF MEDICINAL CHEMISTRY. 2010. 53(9):3465-3479.

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