英文信息

Principal investigator

Name:

Jingpeng GeAssistant Professor , PhD, Assistant Professor

Position:

School of Life Science and Technology

Affiliation:

Honor:

Education Background:

2006/09-2010/07, Jilin University, BS
2011/09-2016/01, Tsinghua University, Ph. D.

Working Experience:

2016/02-2021/10, Vollum Institute, Oregon Health & Science University, Postdoc
2021/11-now, School of Life Sciences and Technology, Assistant Professor

Group Introduction

Research Area:

Structural Biology, Neuroscience

Research Interests:

We use a combination of cryo-EM microscopy, electrophysiology and various biochemical/biophysical tools to investigate the structures, functions and molecular mechanisms of key membrane proteins in nervous system. Our long-term research interests are the following three aspects:

1. How animals sense the physical and chemical stimuli;

2. How membrane proteins regulate in lipid/sugar metabolism in nervous system or neurodegenerative diseases;

3. How membrane proteins mediate the interactions between ER and other membrane systems

Group Website:

Research Achievement

Representative Publications (*First Author, # Corresponding Author)

1. Yingjie Ning*; Ruisheng Xu; Jie Yu^#*; Jingpeng Ge^#; .Structural basis for catalytic mechanism of human phosphatidylserine synthase 1.CELL DISCOVERY. Mar 2025.
2. Ruisheng Xu*; Yingjie Ning*; Fandong Ren; Chenxia Gu; Zhengjiang Zhu; Xuefang Pan; Alexey V. Pshezhetsky^#; Jingpeng Ge^#; Jie Yu^#; .Structure and mechanism of lysosome transmembrane acetylation by HGSNAT.NATURE STRUCTURAL & MOLECULAR BIOLOGY. May 2024.
3. Jingpeng Ge*; Johannes Elferich*; Sepehr Dehghani-Ghahnaviyeh; Zhiyu Zhao; Marc Meadows; Henrique von Gersdorff; Emad Tajkhorshid; Eric Gouaux^#; .Molecular mechanism of prestin electromotive signal amplification.CELL. Sep 2021.
4. Sarah Clark*; Johannes Elferich; Jingpeng Gai; April Goehring; Jaba Mitra; Taekjip Ha; Eric Gouaux^#; .Strategy for Compositional Analysis of the Hair Cell Mechanotransduction Complex Using TIRF Microscopy.MICROSCOPY AND MICROANALYSIS. Aug 2019.
5. Jingpeng Ge*; Johannes Elferich*; April Goehring; Huaying Zhao; Peter Schuck; Eric Gouaux^#; .Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5.ELIFE. Aug 2018.
6. Jingpeng Ge*; Wanqiu Li*; Qiancheng Zhao*; Ningning Li*; Maofei Chen; Peng Zhi; Ruochong Li; Ning Gao^#; Bailong Xiao^#; Maojun Yang^#; .Architecture of the mammalian mechanosensitive Piezo1 channel.NATURE. Sep 2015.
7. Jie Yu*; Jingpeng Ge*; Johanna Heuveling; Erwin Schneider^#; Maojun Yang^#; .Structural basis for substrate specificity of an amino acid ABC transporter.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Apr 2015.
8. Xiaozhe Zhang*; Jingjing Wang*; Yue Feng*; Jingpeng Ge; Wenfei Li; Wending Sun*; Irene Iscla; Jie Yu; Paul Blount; Yang Li^#; Maojun Yang^#; .Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Oct 2012.
9. Yue Feng*; Wenfei Li*; Jian Li*; Jiawei Wang; Jingpeng Ge; Duo Xu; Yanjing Liu; Kaiqi Wu; Qingyin Zeng; Jia-Wei Wu; Changlin Tian; Bing Zhou; Maojun Yang^#; .Structural insight into the type-II mitochondrial NADH dehydrogenases.NATURE. Dec 2012.

Monograph

Patent

Funding

Awards

Research Achievement

Group Member and Photo

Name：Didi Xu

Position：Undergraduate Student

Duration：2022.12-now

Email：xudd1@shanghaitech.edu.cn
Name：CX Gu

Position：Undergraduate Student

Duration：2022.12-now

Email：guchx@shanghaitech.edu.cn
Name：KX Qian

Position：Undergraduate Student

Duration：2022.12-now

Email：qiankx@shanghaitech.edu.cn

Jingpeng Ge, PhDAssistant Professor

Principal investigator

Group Introduction

Research Achievement

Representative Publications (*First Author, # Corresponding Author)

Monograph

Patent

Funding

Awards

Research Achievement

Group Member and Photo