中文信息

1. 孙阳阳*; 马涵慧.表观基因组编辑的研究进展与应用.中国科学:生命科学. 12 Jun 2025. 55(06):1193-1209.

2. He, Xiaohui*; Sun, Yadong; Ma, Hanhui.ParSite is a multicolor DNA labeling system that allows for simultaneous imaging of triple genomic loci in living cells.PLOS BIOLOGY. Jan 2025. 23(1).

3. Liu SY(刘思远)*; Zhao YD(赵英迪)*; Mo QQ(莫淇钦); Sun YD(孙亚东); Ma HH(马涵慧).Engineering CjCas9 for Efficient Base Editing and Prime Editing.CRISPR JOURNAL. 01 Dec 2024. 7(6):395-405.

4. Han, Linxiao*; Hu, Yueer*; Mo, Qiqin*; Yang, Hao; Gu, Feng; Bai, Fang; Sun, Yadong; Ma, Hanhui.Engineering Miniature IscB Nickase for Robust Base Editing with Broad Targeting Range.NATURE CHEMICAL BIOLOGY. Dec 2024. 20(12):1629-1639.

5. Hu, Yueer*; Han, Linxiao*; Mo, Qiqin; Du, Zengming; Jiang, Wei; Wu, Xia; Zheng, Jing; Xiao, Xiao; Sun, Yadong; Ma, Hanhui.Engineering Miniature CRISPR-Cas Un1Cas12f1 for Efficient Base Editing.MOLECULAR THERAPY: NUCLEIC ACIDS. 11 Jun 2024. 35(2).

6. He XH(何晓慧)*; Tan YX(谭宇希); Feng Y(冯颖); Sun YD(孙亚东); Ma HH(马涵慧).Tracking pairwise genomic loci by the ParB–ParS and Noc-NBS systems in living cells.NUCLEIC ACIDS RESEARCH. 22 May 2024. 52(9):4922-4934.

7. Wang XN(王向南)*; Li LY(李凌云)*; Guo L(郭力); Feng Y(冯颖); Du ZM(杜增民); Jiang W(蒋威); Wu X(吴侠); Zheng J(郑静); Xiao X(肖啸); Zheng H(郑辉); Sun YD(孙亚东); Ma HH(马涵慧).Robust miniature Cas-based transcriptional modulation by engineering Un1Cas12f1 and tethering Sso7d.MOLECULAR THERAPY. 03 Apr 2024. 32(4):910-919.

8. Ying Feng*; Li Guo; Chen Yang; Hui Zheng; Xiao Xiao; Hanhui Ma.The local density of H3K9me3 dictates the stability of HP1α condensates-mediated genomic interactions.JOURNAL OF GENETICS AND GENOMICS. 26 Apr 2023. 50(10):776-785.

9. Feng Y(冯颖)*; Liu SY(刘思远)*; Mo QQ(莫淇钦); Xiao X(肖啸); Liu PP(刘朋朋); Ma HH(马涵慧).Enhancing Prime Editing Efficiency and Flexibility with Tethered and Split pegRNAs.PROTEIN & CELL. 15 Jul 2022. 14(4):304-308.

10. Feng, Ying*; Wang, Yao; Wang, Xiangnan; He, Xiaohui; Yang, Chen; Naseri, Ardalan; Pederson, Thoru; Zheng, Jing; Zhang, Shaojie; Xiao, Xiao; Xie, Wei; Ma, Hanhui.Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription.GENOME BIOLOGY. 08 Dec 2020. 21(1).

11. 马涵慧*; 冯颖; 郑静.实现高度可控向三维推进——谈基于CRISPR/Cas基因调控系统突破进展.前沿科学. 2019. 3:24-27.

12. Guo, Lijuan*; Zhao, Yilin*; Zhang, Qian; Feng, Ying; Bi, Lulu; Zhang, Xia; Wang, Teng; Liu, Cong; Ma, Hanhui; Sun, Bo.Stochastically multimerized ParB orchestrates DNA assembly as unveiled by single-molecule analysis.NUCLEIC ACIDS RESEARCH. 09 Sep 2022. 50(16):9294-9305.

13. Ma, Hanhui*; Tu, Li-Chun; Chung, Yu-Chieh; Naseri, Ardalan; Grunwald, David; Zhang, Shaojie; Pederson, Thoru.Cell cycle- and genomic distance-dependent dynamics of a discrete chromosomal region.JOURNAL OF CELL BIOLOGY. May 2019. 218(5):1467-1477.

14. Ma, Hanhui*; Tu, Li-Chun; Chung, Yu-Chieh; Naseri, Ardalan; Grunwald, David; Zhang, Shaojie; Pederson, Thoru.A CRISPR view of the genome in living cells: Cell cycle and genomic distance dependent dynamics of chromosomal loci.Biopolymers and Cell. 2019. 35(3):181-182.

15. Wang, Lijie*; Xue, Wei*; Zhang, Hongxia*; Gao, Runze*; Qiu, Houyuan*; Wei, Jia; Zhou, Lina; Lei, Yun-Ni; Wu, Xiaocheng; Li, Xiao; Liu, Chengfang; Wu, Jing; Chen, Qiubing; Ma, Hanhui; Huang, Xingxu; Cai, Cheguo; Zhang, Ying; Yang, Bei; Yin, Hao; Yang, Li; Chen, Jia.Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations.NATURE CELL BIOLOGY. May 2021. 23(5):552-563.

16. Li, Jianan*; Liu, Zhen*; Huang, Shisheng*; Wang, Xiao; Li, Guanglei; Xu, Yuting; Yu, Wenxia; Chen, Shanshan; Zhang, Yu; Ma, Hanhui; Ke, Zunfu; Chen, Jia; Sun, Qiang; Huang, Xingxu.Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome.CELL RESEARCH. Feb 2019. 29(2):174-176.

17. Ma, Hanhui*; Tu, Li-Chun; Naseri, Ardalan; Chung, Yu-Chieh; Grunwald, David; Zhang, Shaojie; Pederson, Thoru.CRISPR-Sirius: RNA scaffolds for signal amplification in genome imaging.NATURE METHODS. Nov 2018. 15(11):928-+.

18. Ma, Hanhui*; Reyes-Gutierrez, Pablo; Pederson, Thoru.A CRISPR-Based Selective Gene Inhibition Method Reveals Dynamic Features of a Cell Nucleus Nanobody Related to the Disease Myotonic Dystrophy.SMALL METHODS. 2018. 2(9).

19. Chuai, Guohui*; Ma, Hanhui; Yan, Jifang; Chen, Ming; Hong, Nanfang; Xue, Dongyu; Zhou, Chi; Zhu, Chenyu; Chen, Ke; Duan, Bin; Gu, Feng; Qu, Sheng; Huang, Deshuang; Wei, Jia; Liu, Qi.DeepCRISPR: optimized CRISPR guide RNA design by deep learning.GENOME BIOLOGY. 26 Jun 2018. 19(1).

20. Ma, Hanhui*; Tu, Li-Chun; Naseri, Ardalan; Huisman, Maximiliaan; Zhang, Shaojie; Grunwald, David; Pederson, Thoru.Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow.NATURE BIOTECHNOLOGY. 2016. 34(5):528-530.

21. Ma, Hanhui*; Tu, Li-Chun; Naseri, Ardalan; Huisman, Maximiliaan; Zhang, Shaojie; Grunwald, David; Pederson, Thoru.CRISPR-Cas9 nuclear dynamics and target recognition in living cells.JOURNAL OF CELL BIOLOGY. 2016. 214(5):529-537.

22. Ma, Hanhui*; Naseri, Ardalan; Reyes-Gutierrez, Pablo; Wolfe, Scot A.; Zhang, Shaojie; Pederson, Thoru.Multicolor CRISPR labeling of chromosomal loci in human cells.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015. 112(10):3002-3007.

23. Ma, Hanhui*; Reyes-Gutierrez, Pablo; Pederson, Thoru.Visualization of repetitive DNA sequences in human chromosomes with transcription activator-like effectors.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013. 110(52):21048-21053.

24. Ma, Hanhui*; Pederson, Thoru.The nucleolus stress response is coupled to an ATR-Chk1-mediated G2 arrest.MOLECULAR BIOLOGY OF THE CELL. 2013. 24(9):1334-1342.

25. Ma, Hanhui*; McLean, Janel R.; Chao, Lucy Fang-I; Mana-Capelli, Sebastian; Paramasivam, Murugan; Hagstrom, Kirsten A.; Gould, Kathleen L.; McCollum, Dannel.A Highly Efficient Multifunctional Tandem Affinity Purification Approach Applicable to Diverse Organisms.MOLECULAR & CELLULAR PROTEOMICS. 2012. 11(8):501-511.

26. Ma, Hanhui*; Pederson, Thoru.Nucleophosmin is a binding partner of nucleostemin in human osteosarcoma cells.MOLECULAR BIOLOGY OF THE CELL. 2008. 19(7):2870-2875.

27. Ma, Hanhui*; Pederson, Thoru.Nucleostemin: a multiplex regulator of cell-cycle progression.TRENDS IN CELL BIOLOGY. 2008. 18(12):575-579.

28. Ma, Hanhui*; Pederson, Thoru.Depletion of the nucleolar protein nucleostemin causes g1 cell cycle arrest via the p53 pathway.MOLECULAR BIOLOGY OF THE CELL. 2007. 18(7):2630-2635.

29. Ma, HH*; Yang, L; Yang, XY; Xu, ZP; Li, BL.Bacterial expression, purification, and in vitro N-myristoylation of fusion hepatitis B virus preS1 with the native-type N-terminus.PROTEIN EXPRESSION AND PURIFICATION. 2003. 27(1):49-54.

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