课题组长
姓名：
钱友存中科院特聘教授 研究员 博士生导师, PhD, 中科院特聘教授
职务：
所在院所：
生命科学与技术学院、中国科学院上海营养与健康研究所
荣誉称号：
课题组简介
研究内容：
通过小鼠动物模型结合临床病人样本研究炎症相关重大疾病（包括自身免疫病、感染性疾病、肿瘤、糖尿病等）的细胞和分子机制。
代表性论文（*第一作者，#通讯作者）
- 1. Song, Xinyang*; Gao, Hanchao; Lin, Yingying; Yao, Yikun; Zhu, Shu; Wang, Jingjing; Liu, Yan; Yao, Xiaomin; Meng, Guangxun; Shen, Nan; Shi, Yufang; Iwakura, Yoichiro; Qian, Youcun#.Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis.IMMUNITY. 2014. 40(1):14-152.
- 2. Song, Xinyang#*; Qian, Youcun#.Peli1 sets the CNS on fire.NATURE MEDICINE. 2013. 19(5):536-538.
- 3. Zhu, Shu*; Pan, Wen; Song, Xinyang; Liu, Yan; Shao, Xinrui; Tang, Yuanjia; Liang, Dong; He, Dongyi; Wang, Honglin; Liu, Wenjun; Shi, Yufang; Harley, John B.; Shen, Nan#; Qian, Youcun#.The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha.NATURE MEDICINE. 2012. 18(7):1077+.
- 4. Song, Xinyang*; Zhu, Shu; Shi, Peiqing; Liu, Yan; Shi, Yufang; Levin, Steven D.; Qian, Youcun#.IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens.NATURE IMMUNOLOGY. 2011. 12(12):1151+.
- 5. Zhu, Shu*; Pan, Wen; Shi, Peiqing; Gao, Hanchao; Zhao, Fang; Song, Xinyang; Liu, Yan; Zhao, Lihua; Li, Xiaoxia; Shi, Yufang; Qian, Youcun#.Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling.JOURNAL OF EXPERIMENTAL MEDICINE. 2010. 207(12):2647-2662.
|
