中文信息

1. Simeng Zhao*^#; Qiuxiang Yang*; Zehua Yu*; Cenfeng Chu; Shengqi Dai; Hongli Li; Min Diao; Lingyue Feng; Junzi Ke; Yilin Xue; Qifang Zhou; Yan Liu; Hanhui Ma; Chao-Po Lin; Yong-Gang Yao; Guisheng Zhong^#.Deciphering enhancers of hearing loss genes for efficient and targeted gene therapy of hereditary deafness.NEURON. 21 Apr 2025. 113(10).

2. Cai, Yuan*^#; Gu, Yonghao^#; Zhang, Jie; Zhu, Ying; Ma, Zhen; He, Qin; Sun, Yongjia; Yuan, Mengmeng; Li, Xiaojun; Zhu, Kai; Miao, Bolong; Zhao, Jin; Liu, Juan; Tang, Min; Tong, Dali; Feng, Lixia; Ma, Ming^#; Zhong, Guisheng^#; Qiu, Zilong^#; Xue, Tian^#.An Engineered Intravitreal Injection Retinal-Pigment-Epithelium-Tropic Adeno-Associated Virus Vector Expressing a Bispecific Antibody Binding VEGF-A and ANG-2 Rescues Neovascular Age-Related Macular Degeneration in Animal Models and Patients.RESEARCH. 29 May 2025. 8.

3. Gong, Yajun*; Huang, Xianyu; Tu, Tianxiang; Chu, Cenfeng; Xian, Chunrui; Yuan, Yushun; Fu, Xin; Li, Ruobi; Zhong, Guisheng^#; Zhou, Xiaolai^#.A novel AAV Vector for gene therapy of RPE-related retinal degenerative diseases via intravitreal delivery.MOLECULAR NEURODEGENERATION. 25 Nov 2024. 19(1).

4. Qi, Jieyu*^#; Tan, Fangzhi^#; Zhang, Liyan; Zhou, Yinyi; Zhang, Ziyu; Sun, Qiuhan; Li, Nianci; Fang, Yuan; Chen, Xin; Wu, Yunhao; Zhong, Guisheng^#; Chai, Renjie^#.Critical role of TPRN rings in the stereocilia for hearing.MOLECULAR THERAPY. 03 Jan 2024. 32(1):204-217.

5. Zhao, Simeng*; Ke, Junzi; Yang, Boyu; Tan, Fangzhi; Yang, Jie; Lin, Chao Po; Wang, Haopeng^#; Zhong, Guisheng^#.A protective AAV vaccine for SARS-CoV-2.SIGNAL TRANSDUCTION AND TARGETED THERAPY. 05 Sep 2022. 7(1).

6. Li, Hui*; Yang, Jie; Tian, Cuiping; Diao, Min; Wang, Quan; Zhao, Simeng; Li, Shanshan; Tan, Fangzhi; Hua, Tian; Qin, Ya; Lin, Chao-Po; Deska-Gauthier, Dylan; Thompson, Garth J.; Zhang, Ying; Shui, Wenqing; Liu, Zhi-Jie; Wang, Tong; Zhong, Guisheng^#.Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging.NATURE COMMUNICATIONS. 2020. 11(1):5699.

7. Tan, Fangzhi*^#; Chu, Cenfeng*; Qi, Jieyu*; Li, Wenyan*; You, Dan; Li, Ke; Chen, Xin; Zhao, Weidong; Cheng, Cheng; Liu, Xiaoyi; Qiao, Yunbo; Su, Bing; He, Shuijin; Zhong, Chao; Li, Huawei^#; Chai, Renjie^#; Zhong, Guisheng^#.AAV-ie enables safe and efficient gene transfer to inner ear cells.NATURE COMMUNICATIONS. 19 Aug 2019. 10.

8. Liu, Yan*; Qi, Jieyu*; Chen, Xin*; Tang, Mingliang*; Chu, Cenfeng; Zhu, Weijie; Li, Hui; Tian, Cuiping; Yang, Guang; Zhong, Chao; Zhang, Ying; Ni, Guangjian; He, Shuijin^#; Chai, Renjie^#; Zhong, Guisheng^#.Critical role of spectrin in hearing development and deafness.SCIENCE ADVANCES. Apr 2019. 5(4).

9. Tao, Yong*; Liu, Xiaoyi; Yang, Liu; Chu, Cenfeng; Tan, Fangzhi; Yu, Zehua; Ke, Junzi; Li, Xiang; Zheng, Xiaofei; Zhao, Xingle; Qi, Jieyu; Lin, Chao Po; Chai, Renjie^#; Zhong, Guisheng^#; Wu, Hao^#.AAV-ie-K558R mediated cochlear gene therapy and hair cell regeneration.SIGNAL TRANSDUCTION AND TARGETED THERAPY. 22 Apr 2022. 7(1).

10. Lan, Yiyang*; Tao, Yong; Wang, Yunfeng; Ke, Junzi; Yang, Qiuxiang; Liu, Xiaoyi; Su, Bing; Wu, Yiling; Lin, Chao-Po; Zhong, Guisheng^#.Recent development of AAV-based gene therapies for inner ear disorders.GENE THERAPY. Aug 2020.

11. Li, Shanshan*; Luo, Huoqing; Lou, Ronghui; Tian, Cuiping; Miao, Chen; Xia, Lisha; Pan, Chen; Duan, Xiaoxiao; Dang, Ting; Li, Hui; Fan, Chengyu; Tang, Pan; Zhang, Zhuangzhuang; Liu, Yan; Li, Yunxia; Xu, Fei; Zhang, Yaoyang; Zhong, Guisheng^#; Hu, Ji^#; Shui, Wenqing^#.Multiregional profiling of the brain transmembrane proteome uncovers novel regulators of depression.SCIENCE ADVANCES. 2021. 7(30):eabf0634.

12. Qiao, Yunbo*^#; Wang, Zejian*; Tan, Fangzhi*; Chen, Jun*; Lin, Jianxiang; Yang, Jie; Li, Hui; Wang, Xiongjun; Sali, Andrej; Zhang, Liye^#; Zhong, Guisheng^#.Enhancer Reprogramming within Pre-existing Topologically Associated Domains Promotes TGF-beta-Induced EMT and Cancer Metastasis.MOLECULAR THERAPY. 02 Sep 2020. 28(9):2083-2095.

13. Zhang, Bingjie*; Zhao, Simeng; Yang, Dehua; Wu, Yiran; Xin, Ye; Cao, Haijie; Huang, Xi-Ping; Cai, Xiaoqing; Sun, Wen; Ye, Na; Xu, Yueming; Peng, Yao; Zhao, Suwen; Liu, Zhi-Jie; Zhong, Guisheng^#; Wang, Ming-Wei^#; Shui, Wenqing^#.A novel G protein-biased and subtype-selective agonist for a G protein-coupled receptor discovered from screening herbal extracts.ACS CENTRAL SCIENCE. 2020. 6(2):213-225.

14. Chen, Xiaoyu*; Xu, Yueming; Qu, Lu; Wu, Lijie; Han, Gye Won; Guo, Yu; Wu, Yiran; Zhou, Qingtong; Sun, Qianqian; Chu, Cenfeng; Yang, Jie; Yang, Liu; Wang, Quan; Yuan, Shuguang; Wang, Ling; Hu, Tao; Tao, Houchao; Sun, Yaping; Song, Yunpeng; Hu, Liaoyuan; Liu, Zhi-Jie; Stevens, Raymond C.; Zhao, Suwen^#; Wu, Dong^#; Zhong, Guisheng^#.Molecular Mechanism for Ligand Recognition and Subtype Selectivity of alpha(2C) Adrenergic Receptor.CELL REPORTS. 03 Dec 2019. 29(10):2936-+.

15. Qi, Jieyu*; Liu, Yan*; Chu, Cenfeng; Chen, Xin; Zhu, Weijie; Shu, Yilai; He, Shuijin^#; Chai, Renjie^#; Zhong, Guisheng^#.A cytoskeleton structure revealed by super-resolution fluorescence imaging in inner ear hair cells.CELL DISCOVERY. 19 Feb 2019. 5.

16. Xu, Ke*; Zhong, Guisheng; Zhuang, Xiaowei^#.Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons.SCIENCE. 2013. 339(6118):452-456.

17. Zhong, Guisheng*; Sharma, Kamal; Harris-Warrick, Ronald M.^#.Frequency-dependent recruitment of V2a interneurons during fictive locomotion in the mouse spinal cord.NATURE COMMUNICATIONS. 2011. 2.

18. Qu, Lu*; Zhou, Qingtong; Xu, Yueming; Guo, Yu; Chen, Xiaoyu; Yao, Deqiang; Han, Gye Won; Liu, Zhi-Jie; Stevens, Raymond C.; Zhong, Guisheng^#; Wu, Dong^#; Zhao, Suwen^#.Structural Basis of the Diversity of Adrenergic Receptors.CELL REPORTS. 03 Dec 2019. 29(10):2929-+.

19. Zhao, Simeng*; Liu, Fengjiang; Qiu, Shizhen; Lan, Qiaoshuai; Wu, Yiran; Xu, Wei; Ke, Junzi; Yang, Jie; Liu, Xiaoyan; Wang, Kun; Guo, Hangtian; Xia, Shuai; Zhang, Fangfang; Wang, Jiabei; Hu, Xiaowen; Lu, Lu; Jiang, Shibo; Zhao, Suwen; Liu, Lianxin^#; Xie, Youhua^#; Yang, Xiuna^#; Wang, Haopeng^#; Zhong, Guisheng^#.A core epitope targeting antibody of SARS-CoV-2.PROTEIN & CELL. 20 Jan 2023. 14(1).

20. Chu, Cenfeng*; Zhang, Huifang; Jia, Guodong; Zhong, Guisheng.Developing Novel AAV Capsids for Ophthalmic Gene Therapy.MOLECULAR THERAPY. 01 May 2023. 31(4).

21. Fan, Ke-qi*; Li, Yi-yuan; Wang, Hao-li; Mao, Xin-tao; Guo, Jin-xin; Wang, Fei; Huang, Ling-jie; Li, Yi-ning; Ma, Xiang-yu; Gao, Zheng-jun; Chen, Wei; Qian, Dan-dan; Xue, Wen-jin; Cao, Qian; Zhang, Lei; Shen, Li; Zhang, Long; Tong, Chao; Zhong, Jiang-yan; Lu, Wei; Lu, Ling; Ren, Ke-ming; Zhong, Guisheng; Wang, Yuan; Tang, Mingliang; Feng, Xin-hua; Chai, Ren-jie^#; Jin, Jin^#.Stress-Induced Metabolic Disorder in Peripheral CD4(+) T Cells Leads to Anxiety-like Behavior.CELL. 31 Oct 2019. 179(4):864-+.

22. Zhao, Yanan*; Wu, Xuanyuan*; Chen, Xin; Li, Jianan; Tian, Cuiping; Chen, Jiangrui; Xiao, Cheng; Zhong, Guisheng^#; He, Shuijin^#.Calcineurin Signaling Mediates Disruption of the Axon Initial Segment Cytoskeleton after Injury.ISCIENCE. 21 Feb 2020. 23(2).

23. Shim, Sang-Hee*; Xia, Chenglong; Zhong, Guisheng; Babcock, Hazen P.; Vaughan, Joshua C.; Huang, Bo; Wang, Xun; Xu, Cheng; Bi, Guo-Qiang^#; Zhuang, Xiaowei^#.Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012. 109(35):13978-13983.

24. Zhong, Guisheng*; Shevtsova, Natalia A.; Rybak, Ilya A.; Harris-Warrick, Ronald M.^#.Neuronal activity in the isolated mouse spinal cord during spontaneous deletions in fictive locomotion: insights into locomotor central pattern generator organization.JOURNAL OF PHYSIOLOGY-LONDON. 2012. 590(19):4735-4759.

25. Zhong, Guisheng*; Droho, Steven; Crone, Steven A.; Dietz, Shelby; Kwan, Alex C.; Webb, Watt W.; Sharma, Kamal; Harris-Warrick, Ronald M.^#.Electrophysiological Characterization of V2a Interneurons and Their Locomotor-Related Activity in the Neonatal Mouse Spinal Cord.JOURNAL OF NEUROSCIENCE. 2010. 30(1):170-182.

26. Crone, Steven A.*; Zhong, Guisheng; Harris-Warrick, Ronald^#; Sharma, Kamal^#.In Mice Lacking V2a Interneurons, Gait Depends on Speed of Locomotion.JOURNAL OF NEUROSCIENCE. 2009. 29(21):7098-7109.

27. Yu, Jing*; Liu, Zaizhou; Liang, Yuanyuan; Luo, Feng; Zhang, Jie; Tian, Cuiping; Motzik, Alex; Zheng, Mengmeng; Kang, Jingwu; Zhong, Guisheng; Liu, Cong; Fang, Pengfei; Guo, Min; Razin, Ehud^#; Wang, Jing^#.Second messenger Ap(4)A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells.NATURE COMMUNICATIONS. 11 Oct 2019. 10.

28. Hao, Kaili*; Lei, Wei; Wu, Hongchun; Wu, Jie; Yang, Zhuangzhuang; Yan, Shiping; Lu, Xing-Ai; Li, Jingjing; Xia, Xue; Han, Xinglong; Deng, Wenbo; Zhong, Guisheng; Zhao, Zhen-Ao; Hu, Shijun^#.LncRNA-Safe contributes to cardiac fibrosis through Safe-Sfrp2-HuR complex in mouse myocardial infarction.THERANOSTICS. 2019. 9(24):7282-7297.

29. An, Bolin*; Wang, Xinyu*; Cui, Mengkui; Gui, Xinrui; Mao, Xiuhai; Liu, Yan; Li, Ke; Chu, Cenfeng; Pu, Jiahua; Ren, Susu; Wang, Yanyi; Zhong, Guisheng; Lu, Timothy K.; Liu, Cong; Zhong, Chao^#.Diverse Supramolecular Nanofiber Networks Assembled by Functional Low-Complexity Domains.ACS NANO. Jul 2017. 11(7):6985-6995.

30. Peng Yao*; Zhao Simeng; Wu Yiran; Cao Haijie; Xu Yueming; Liu Xiaoyan; Shui Wenqing; Cheng Jianjun; Zhao Suwen; Shen Ling; Ma Jun; Quinn Ronald J; Raymond C. Stevens; Zhong Guisheng^#; Liu Zhijie^#.Identification of natural products as novel ligands for the human 5-HT_(2C) receptor.BIOPHYSICSREPORTS. 2018. 4(1):50-61.

31. Lu, Yao*; Qiu, Ying; Chen, Peng; Chang, Haishuang; Guo, Luqiang; Zhang, Fang; Ma, Li; Zhang, Chi; Zheng, Xin; Xiao, Jun; Zhong, Ruiyue; Han, Lei; Xu, Xiaoyan; Zhang, Yanbo; Li, Dangsheng; Zhong, Guisheng; Boyton, Rosemary; Huang, Ying; He, Yongning; Hu, Ronggui^#; Wei, Bin^#; Wang, Hongyan^#.ER-localized Hrd1 ubiquitinates and inactivates Usp15 to promote TLR4-induced inflammation during bacterial infection.NATURE MICROBIOLOGY. Dec 2019. 4(12):2331-2346.

32. Zhong, Guisheng*; He, Jiang; Zhou, Ruobo; Damaris Lorenzo; Hazen P Babcock; Vann Bennett; Zhuang, Xiaowei^#.Developmental mechanism of the periodic membrane skeleton in axons.ELIFE. 23 Dec 2014.

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