Principal investigator
Name:
Min ZhuangAssociate Professor , PhD, Associate Professor
Position:
Affiliation:
School of Life Science and Technology
Honor:
Group Introduction
Research Area:
Ubiquitination
Research Interests:
| We are using a multi-disciplinary approach to study membrane-based ubiquitin ligases and their role in regulating organelle function. |
Representative Publications (*First Author, # Corresponding Author)
- 1. Yue, Suyu*; Xu, Peng; Cao, Zhihe; Zhuang, Min#.PUP-IT2 as an alternative strategy for PUP-IT proximity labeling.Frontiers in Molecular Biosciences. 29 September 2022. 9, 1007720.
- 2. Huo, Yinbo*; Sun, Weiping; Shi, Tiezhu; Gao, Song; Zhuang, Min#.The MFN1 and MFN2 mitofusins promote clustering between mitochondria and peroxisomes.COMMUNICATIONS BIOLOGY. 06 May 2022. 5(5):423.
- 3. Zheng Jun*; Chen Xi#*; Li Qiang; Zhong Guisheng; Zhuang Min#.Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy.JOURNAL OF CELL BIOLOGY. 08 Nov 2021. 221(1):-.
- 4. Sun, Weiping*; Huo, Yinbo; Mei, Yuxuan; Zhou, Qingtong; Zhao, Suwen; Zhuang, Min#.Identification of a Small Probe That Can Be Conjugated to Proteins by Proximity Labeling.ACS CHEMICAL BIOLOGY. Jan 2020. 15(1):39-43.
- 5. Zhang Ziheng*; Sun Weiping*; Shi Tiezhu*; Lu Pengfei#; Zhuang Min#; Liu Ji-Long#.Capturing RNA-protein Interaction via CRUIS.NUCLEIC ACIDS RESEARCH. 06 Mar 2020. 48(9):e52.
- 6. Liu, Qiang*; Zheng, Jun; Sun, Weiping; Huo, Yinbo; Zhang, Liye; Hao, Piliang; Wang, Haopeng#; Zhuang, Min#.A proximity-tagging system to identify membrane protein-protein interactions.NATURE METHODS. Sep 2018. 15(9):715-+.
- 7. Zhang, Yanchun*; Xiong, Xuexue*; Zhu, Qi; Zhang, Jiali; Chen, Shengmiao; Wang, Yuetong; Cao, Jian; Chen, Li; Hou, Linjun; Zhao, Xi; Hao, Piliang; Chen, Jian; Zhuang, Min; Li, Dake#; Fan, Gaofeng#.FER-mediated phosphorylation and PIK3R2 recruitment on IRS4 promotes AKT activation and tumorigenesis in ovarian cancer cells.ELIFE. 12 May 2022. 11.
- 8. Xie, Shu*; Li, Haixiang; Yao, Fenyong; Huang, Jiechang; Yang, Xiaomei; Chen, Xin; Liu, Qiang; Zhuang, Min; He, Shuijin.PUPIL enables mapping and stamping of transient electrical connectivity in developing nervous systems.CELL REPORTS. 2021. 37(3).
- 9. Chu, Yuanyuan*; Dong, Xingqi; Kang, Yingjin; Liu, Jingnan; Zhang, Tao; Yang, Cuiwei; Wang, Zhangshun; Shen, Wangchen; Huo, Huanhuan; Zhuang, Min; Lu, Junxia#; Liu, Yanfen#.The chaperone BAG6 regulates cellular homeostasis between autophagy and apoptosis by holding LC3B.ISCIENCE. Oct 2020. 23(11).
- 10. Zhang, Kun*; Cheng, Xiaoting*; Zhao, Liping*; Huang, Mingqian; Tao, Yong; Zhang, Hongbo; Rosenholm, Jessica M.; Zhuang, Min; Chen, Zheng-Yi; Chen, Bing#; Shu, Yilai#.Direct Functional Protein Delivery with a Peptide into Neonatal and Adult Mammalian Inner Ear In Vivo.MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. 11 Sep 2020. 18:511-519.
- 11. Wang, Yuetong*; Cao, Jian; Liu, Weiwei; Zhang, Jiali; Wang, Zuo; Zhang, Yiqun; Hou, Linjun; Chen, Shengmiao; Hao, Piliang; Zhang, Liye; Zhuang, Min; Yu, Yang; Li, Dake; Fan, Gaofeng#.Protein tyrosine phosphatase receptor type R (PTPRR) antagonizes the Wnt signaling pathway in ovarian cancer by dephosphorylating and inactivating βcatenin.JOURNAL OF BIOLOGICAL CHEMISTRY. Nov 2019. 294(48):18306-18323.
- 12. Julien, Olivier*; Zhuang, Min; Wiita, Arun P.; O'Donoghue, Anthony J.; Knudsen, Giselle M.; Craik, Charles S.; Wells, James A.#.Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 05 Apr 2016. 113(14):E2001-E2010.
- 13. Ke, Qiong*; Li, Weiqiang; Lai, Xingqiang; Chen, Hong; Huang, Lihua; Kang, Zhuang; Li, Kai; Ren, Jie; Lin, Xiaofeng; Zheng, Haiqing; Huang, Weijun; Ma, Yunhan; Xu, Dongdong; Chen, Zheng; Song, Xinming; Lin, Xinyi; Zhuang, Min; Wang, Tao; Zhuang, Fengfeng; Xi, Jianzhong; Mao, Frank Fuxiang; Xia, Huimin; Lahn, Bruce T.; Zhou, Qi#; Yang, Shihua#; Xiang, Andy Peng#.TALEN-based generation of a cynomolgus monkey disease model for human microcephaly.CELL RESEARCH. Sep 2016. 26(9):1048-1061.
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