英文信息

Principal investigator

Name:

Zhi ZhouAssistant Professor , PhD, Assistant Professor

Position:

Affiliation:

School of Life Science and Technology

Honor:

Education Background:

Working Experience:

Group Introduction

Research Area:

Mammalian Germ Cell Development

Research Interests:

Failure of gametogenesis causes clinical infertility; our current interests focus on germ cell development, a) by using spermatogonial stem cell model, we would like to uncover the mechanisms of adult stem cell maintenance and differentiation; b) by using transgenic mouse model, we are trying to figure out the functions of some new genes during meiosis and their working mechanisms.

Group Website:

Research Achievement

Representative Publications (*First Author, # Corresponding Author)

1. Zhao, Liangyu*; Yao, Chencheng; Zhu, Zijue; Liu, Nachuan; Zhai, Jing; Wang, Yizhou; Yang, Chao; Tian, Ruhui; Li, Peng; Chen, Huixing; Wan, Zhong; Zhi, Erlei; Huang, Yuhua; Zhou, Zhi^#; Li, Zheng^#.Intra-Seminiferous Tubular Injection of Vascular Endothelial Growth Factor C Sustained-Release Ultrafine Particles: A Novel Method for Improving the Regeneration of Spermatogenesis After Chemotherapy.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY. Dec 2019. 15(12):2376-2392.
2. Zhou, Zhi*; Kawabe, Hiroshi; Suzuki, Atsushi; Shinmyozu, Kaori; Saga, Yumiko^#.NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes.NATURE COMMUNICATIONS. 06 Jun 2017. 8.
3. Zhou, Zhi*; Shirakawa, Takayuki; Ohbo, Kazuyuki; Sada, Aiko; Wu, Quan; Hasegawa, Kazuteru; Saba, Rie; Saga, Yumiko^#.RNA Binding Protein Nanos2 Organizes Post-transcriptional Buffering System to Retain Primitive State of Mouse Spermatogonial Stem Cells.DEVELOPMENTAL CELL. 2015. 34(1):96-107.
4. Suzuki, Atsushi^#*; Niimi, Yuki; Shinmyozu, Kaori; Zhou, Zhi; Kiso, Makoto; Saga, Yumiko^#.Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development.EMBO REPORTS. 2016. 17(1):37-46.
5. Wu, Quan*; Fukuda, Kurumi; Kato, Yuzuru; Zhou, Zhi; Deng, Chu-Xia; Saga, Yumiko^#.Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming.PLOS BIOLOGY. 2016. 14(9).
6. Zhou, Z.*; Zhang, Q.; Lu, X.; Wang, R.; Wang, H.^#; Wang, Y-L; Zhu, C.; Lin, H-Y^#; Wang, H.^#.The proprotein convertase furin is required for trophoblast syncytialization.CELL DEATH & DISEASE. 2013. 4.
7. Zhou, Z.*; Wang, R.; Yang, X.; Lu, X. -Y.; Zhang, Q.; Wang, Y. -L.; Wang, H.^#; Zhu, C.; Lin, H. -Y.^#; Wang, H.^#.The cAMP-responsive element binding protein (CREB) transcription factor regulates furin expression during human trophoblast syncytialization.PLACENTA. 2014. 35(11):907-918.
8. Zhang, Q.*; Chen, Q.; Lu, X.; Zhou, Z.; Zhang, H.; Lin, H-Y; Duan, E.; Zhu, C.; Tan, Y.^#; Wang, H.^#.CUL1 promotes trophoblast cell invasion at the maternal-fetal interface.CELL DEATH & DISEASE. 2013. 4.
9. Zhou, Z.*; Shen, T.; Zhang, B. -H.; Lv, X. -Y.; Lin, H. -Y.; Zhu, C.; Xue, L. -Q.^#; Wang, H.^#.The proprotein convertase furin in human trophoblast: Possible role in promoting trophoblast cell migration and invasion.PLACENTA. 2009. 30(11):929-938.

Zhi Zhou, PhDAssistant Professor

Principal investigator

Group Introduction

Research Achievement

Representative Publications (*First Author, # Corresponding Author)

Monograph

Patent

Funding

Awards

Research Achievement

Group Member and Photo