科研成果

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科研成果

Discovery of a INSIG binding compound that ameliorates nonalcoholic steatohepatitis by inhibiting SREBP-mediated lipogenesis 2022-01-31
Towards precise large genomic fragment deletion 2021-12-03
Tumor evolution selectively inactivates the core microRNA machinery for immune evasion 2021-12-01
Efficient DNA interrogation of SpCas9 governed by its electrostatic interaction with DNA beyond the PAM and protospacer 2021-11-25
Surfaceome CRISPR screen identifies OLFML3 as a rhinovirus-inducible IFN antagonist 2021-10-22
Editing Properties of Base Editors with SpCas9-NG in Discarded Human Tripronuclear Zygotes 2021-10-15
Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations. 2021-05-10
Correction of the pathogenic mutation in TGM1 gene by adenine base editing in mutant embryos 2021-05-08

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