We are looking for an ambitious, highly-driven postdoctoral scientist to work with Dr Kimata to elucidate the functions of the cell cycle-regulating proteins in coupling cell cycle exit to cell fate determination and cellular differentiation during the metazoan development. The Kimata lab aims to understand the molecular and cellular mechanisms by which the cell cycle is coordinated with developmental and homeostatic processes in the metazoan organism. We combine the model systems of Drosophila melanogaster and mammalian organoids with in vitro cell culture, biochemistry, proteomics and bioinformatics, and have been working with international collaborators. The focus of our research has been on the evolutionarily conserved multisubunit ubiquitin ligase, the anaphase promoting complex/cyclosome (APC/C).
We have recently discovered:
1)APC/C regulates the transcriptional activity of one of the major extracellular signalling pathways, the Wnt signalling pathway, during the retinal development in Drosophila (Martins et al., 2017 Developmental Cell);
2)APC/C ensures cell fate determination of the neural stem cell and the oocyte through the regulation of the centrosome (Meghini et al., 2016, Nature Communications, Braun et al., bioRxiv).
Postdoctoral Research Fellow in Prof. Yuu Kimata's Laboratory | |
To design the course of research projects under the guidance of Dr Kimata. To design experiments and conduct them accurately and reproducibly. To analyse and interpret data objectively and critically. To report and discuss results with Dr Kimata and other lab members. To present the work at internal and external seminars and at national and international scientific conferences. To contribute to the preparation of publications and applications for funding. To assist Dr Kimata with supervision of students and/or junior research staff working in support of the projects. To cooperate with Dr Kimata and lab members in organising lab regents and equipment and in maintaining high standard of the lab space. | |
The successful candidate will have a strong track record and will demonstrate excellent inter-personal, organisational and time management skills and good English communication skills. An individual with a strong passion for science and collaborative and can-do attitudes will best fit to our lab. Applications from adventurous foreign individuals are also highly encouraged. | |
Compensation and Benefits | |
The annual salary will be decided based on the University salary scale, and the experience and qualification of the candidate. All postdocs in ShanghaiTech will have access to various social benefits provided by the university, including an in-campus accommodation and a contribution to the social security. The initial term of this post is 24 months, but the term can be extended up to 4 years, with the possibility of the promotion to Research Assistant Professor. | |
Application | |
Qualified applicants are requested to provide the following items (in English): 1. A cover letter describing your interests and professional goals 2. Curriculum Vitae including academic background and work experience 3. List of publications and PDF files of three best papers (if applicable) 4. Contact details of two or three referees, one of which must be your most recent supervisor/line manager. References will be requested after the initial selection. Applicants who are interested in this position should submit the above documents directly to Dr Yuu Kimata via e-mail: yKimata@shanghaitech.edu.cn. At the same time, applicants should also complete the online application form using the Shanghai University of Science and Technology Talent Recruitment System ( http://jobs.shanghaitech.edu.cn/ ) following the instruction. Shortlisted candidates will be contacted and interviewed by Dr Kimata. |