INTRODUCTION INTRODUCTION

  • Gene Editing Center (GEC) seeks to perform innovative research and develop new technologies with intellectual property rights and translational potentials. GEC also builds up an international team of research and professionals familiar to the policies and regulations of the biomedical industry. According to national strategicplan in gene editing field, GEC will focus on development of gene editing tools, delivery and preparation of gene editing vectors, gene editing therapy, rapid detection of virus and CRISPR mechanism. In the future, GEC aims to become a comprehensive and international innovation center in the gene editing field.

RESEARCH AREA RESEARCH AREA

1

  • Development of high precision editing tool
  • High-efficiency and high-accuracy single base editing system
  • Optimization of gene modification system with improved efficiency

2

  • Gene editing therapy
  • Gene editing therapy for thalassemia
  • Gene editing therapy for juvenile macular malnutrition

3

  • Preparation and delivery of gene editing vector
  • Delivery of novel gene modification tools by non-viral vectors
  • Exploring chemical modification of new gene modification tools

4

  • Rapid detection of virus
  • Design and synthesis of crRNA library
  • Screening of suitable Cas13 homologs and optimization
  • Optimization of nucleic acid amplification system
  • Optimization of crRNA
  • Optimization of nucleic acid cleavage system

5

  • Exploration, improvement and application of CRISPR system
  • Exploration of CRISPR activity and mechanism
  • Engineering of Cas protein
  • Application of molecular mechanism
  • Drug target screening

SCIENTIFIC & ADMINISTRATIVE COMMITTEE SCIENTIFIC & ADMINISTRATIVE COMMITTEE

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